2865822-82-6
2865822-82-6
Chemical Structure
Denikitug
Synonym(s): GS-1811; JTX-1811
- CAS No.: 2865822-82-6
- Formula:N/A
- Molecular Weight:(147.2 kDa)
SMILES: [Denikitug]
Biological Activity: Denikitug (GS-1811; JTX-1811) is a humanized monoclonal antibody against CCR8 receptor with a KD of 16.8 pM. Denikitug specifically binds to human CCR8, inhibits CCL1-induced downstream CCR8 signaling. Denikitug selectively depletes cells expressing CCR8 via antibody-dependent cellular cytotoxicity (ADCC). Denikitug promotes anti-tumor immunity and can be used for the research of cancer and immunology[1].
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Denikitug | 99.00% | Denikitug (GS-1811; JTX-1811) is a humanized monoclonal antibody against CCR8 receptor with a KD of 16.8 pM. Denikitug specifically binds to human CCR8, inhibits CCL1-induced downstream CCR8 signaling. Denikitug selectively depletes cells expressing CCR8 via antibody-dependent cellular cytotoxicity (ADCC). Denikitug promotes anti-tumor immunity and can be used for the research of cancer and immunology. | ||||||||||||||||||||
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References
Keywords
