39 Results for "

CD40 ligand

" in MedChemExpress (MCE) Product Catalog:
Products (39)

39 Results for "CD40 ligand" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P72907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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2
2 Cited Publications
Cat. No.: HY-P72908
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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1
1 Cited Publications
Cat. No.: HY-P99842A
CAS No.: 1416147-64-2

Research Areas:  

Inflammation/Immunology

Dapirolizumab is an antibody targeting CD40L (CD154). Dapirolizumab can be used in research related to systemic lupus erythematosus .
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1
1 Cited Publications
Cat. No.: HY-P7144
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-P990083
CAS No.: 2628092-47-5
Synonyms: AT-1501

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (AT-1501) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P99625
CAS No.: 2515463-86-0
Synonyms: SAR441344; INX-021

Target:  

TNF Receptor

Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sj gren’s syndrome and type I diabetes research .
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Cat. No.: HY-P99325
CAS No.: 252662-47-8
Synonyms: IDEC-131; Anti-Human CD40 ligand Recombinant Antibody

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab is an immunosuppressive agent. Toralizumab can lead to increased thrombosis. Toralizumab can be studied in research for diseases such as multiple sclerosis, systemic lupus erythematosus (SLE), and Crohn’s disease .
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Cat. No.: HY-P99845
CAS No.: 2245953-10-8
Synonyms: MEDI 4920; VIB 4920

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Dazodalibep (MEDI 4920; VIB 4920) is a non-antibody fusion protein that targets CD40L. Dazodalibep inhibits the co-stimulatory signals between immune cells (such as T cells, B cells, and antigen-presenting cells), thereby enabling the inhibition of a broader range of cellular and humoral responses. Dazodalibep can be used for research on rheumatoid arthritis and Sjögren's syndrome .
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Cat. No.: HY-P99257
CAS No.: 1453067-91-8
Synonyms: ASKP 1240

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (Kd: 0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection .
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Cat. No.: HY-P991557

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

ABI793 is a human IgG1 anti-human CD154 (CD40 ligand) monoclonal antibody. ABI793 inhibits immune response by blocking the CD154-CD40 (IC50 = 75 nM) signaling pathway. ABI793 effectively prevents kidney transplant rejection. ABI793 can be used for research on immunological rejection .
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Cat. No.: HY-174737
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CD40LG mRNA encodes the human CD40 ligand (CD40LG) protein, a protein that is expressed on the surface of T cells. CD40LG regulates B cell function by engaging CD40 on the B cell surface.
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Cat. No.: HY-P990083A
CAS No.: 2628092-47-5
Synonyms: AT-1501 (powder)

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Tegoprubart (powder) (AT-1501 (powder)) is a CD40 ligand inhibitor (EC50=100 ng/mL) and immunosuppressant that selectively inhibits the CD40 ligand, a co-stimulatory molecule involved in T cell activation. Tegoprubart (powder) suppresses immune rejection, prevents rejection in animal transplantation models, and reduces cell-mediated and antibody-mediated immune responses to create a more immunotolerant environment. Tegoprubart (powder) preserves renal function when combined with Mycophenolate (HY-B0421) and Corticosteroids, and maintains graft function in preclinical studies. Tegoprubart (powder) is applicable to research related to kidney transplantation and kidney transplant rejection .
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Cat. No.: HY-P705466
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40-L; T-cell antigen Gp39; TNF-related activation protein; TRAP; TRAP; Tumor necrosis factor ligand superfa; CD40 ligand; CD154; CD40lg; CD40l; Tnfsf5
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Cat. No.: HY-P72122
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-P72121
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-D1236
CAS No.: 16090-02-1
Fluorescent brightener 71 (FB71) is an inhibitor targeting deubiquitinases UCHL5 and USP14, as well as a CD40 ligand. Fluorescent brightener 71 blocks enzymatic activity, induces apoptosis, inhibits cell growth and triggers reactive oxygen species production. Meanwhile, Fluorescent brightener 71 upregulates the expression of oxidative stress-related genes gpx-4 and sod-4, and reversibly increases the protein levels of UCHL5 and USP14 through a feedback response. Fluorescent brightener 71 inhibits the growth, movement and reproductive capacity of Caenorhabditis elegans, and also exhibits concentration-dependent toxic effects. Fluorescent brightener 71 can be applied to scientific research in related fields such as breast cancer .
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Cat. No.: HY-P72907AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-P78934
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-P71910
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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Cat. No.: HY-P70609
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD40LG; T-BAM; Prev. TNFSF5; Tumor Necrosis Factor (ligand) Superfamily Member 5; Prev. HIGM1; Tumor Necrosis Factor ligand Superfamily Member 5; Prev. IMD3; T-B Cell-Activating Molecule; CD40-L; CD40 Antigen ligand; CD40L; T-Cell Antigen Gp39; TRAP; Tumo
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