10 Results for "

CF-1 Mice

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "CF-1 Mice" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P2329
CAS No.: 9011-93-2
Target:  

Bacterial Antibiotic

Research Areas:  

Infection Inflammation/Immunology

Lysostaphin is an antistaphylococcal agent. Lysostaphin has activities of three enzymes namely, glycylglycine endopeptidase, endo-β-N-acetyl glucosamidase and N-acteyl muramyl-L-alanine amidase .
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Cat. No.: HY-103537A
CAS No.: 1257396-73-8
Target:  

γ-secretase Amyloid-β

Research Areas:  

Neurological Disease

BIIB042 is a potent, orally active, brain-penetrant, and selective γ-secretase modulator (GSM). BIIB042 reduces Aβ42 and increases Aβ38 levels in cells. BIIB042 significantly reduces brain Aβ42 levels in CF-1 mice and Fischer rats, as well as plasma Aβ42 levels in cynomolgus monkeys. BIIB042 reduces Aβ42 levels and Aβ plaque burden in Tg2576 mice. BIIB042 can be used for alzheimer's disease (AD) research .
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Cat. No.: HY-121469
CAS No.: 702-54-5
Purity:  ≥98.0%
Target:  

Others

Research Areas:  

Neurological Disease

Dioxone is a substance possessing convulsant properties qualitatively similar to leptazol and bemegride. Dioxone is orally active .
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Cat. No.: HY-123280
CAS No.: 25451-53-0
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

SCH 54388 is an orally active metabolite of Felbamate (HY-B0184). SCH 54388 significantly attenuates the functional impairment effects induced by Scopolamine (HY-N0296) or Dizocilpine (HY-15084B). SCH 54388 can be used in research related to cognitive impairment .
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Cat. No.: HY-113619
CAS No.: 186293-38-9
Target:  

Bacterial

Research Areas:  

Infection

ABT-255 free base is an orally active anti-bacterial agent. ABT-255 free base exhibits potent in vitro potency (MIC = 0.016-0.031 μg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 free base shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 free base can be used for the study of pulmonary tuberculosis .
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Cat. No.: HY-113619A
CAS No.: 181141-52-6
Target:  

Bacterial

Research Areas:  

Infection

ABT-255 hydrochloride is an orally active anti-bacterial agent. ABT-255 hydrochloride exhibits potent in vitro potency (MIC = 0.016-0.031 μg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 hydrochloride shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 hydrochloride can be used for the study of pulmonary tuberculosis .
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Cat. No.: HY-184859
CAS No.: 83704-55-6
Target:  

Others

Research Areas:  

Others

1,3,4,6,8-Pentachlorodibenzofuran is a pentachlorinated dibenzofuran congener. 1,3,4,6,8-Pentachlorodibenzofuran exhibits acute toxicity in CF-1 mice. 1,3,4,6,8-Pentachlorodibenzofuran can be used in environmental toxicology research .
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Cat. No.: HY-N12398
CAS No.: 52617-25-1
Psychotridine is a natural alkaloid isolated from Psychotria colorata, reveals an analgesic activity in nervous system and an inhibitory efficacy towards platelet aggregation .
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Cat. No.: HY-N8250
CAS No.: 928205-59-8
cis-THSG is a selective and orally active DNA topoisomerase II inhibitor with no activity against DNA topoisomerase I. cis-THSG suppresses transcription of PEPCK. cis-THSG reduces blood glucose levels, ameliorates glucose intolerance, and alleviates insulin resistance in high fat diet-induced diabetic male CF-1 mice. cis-THSG can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-162033
CAS No.: 1030097-65-4
Target:  

Chloride Channel

Research Areas:  

Others

PAT1inh-A0030 is a selective PAT1 (SLC26A6) inhibitor (IC50= 1.0 μM). PAT1inh-A0030 inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption. PAT1inh-A0030 can be used in the study of intestinal diseases related to CF .
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