181141-52-6
Chemical Structure
ABT-255 hydrochloride
- CAS No.: 181141-52-6
- Formula:C21H25ClFN3O3
- Molecular Weight:421.89
IUPAC Name: 1-cyclopropyl-7-fluoro-9-methyl-8-((4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-4H-quinolizine-3-carboxylic acid hydrochloride
InChIKey: UTKJBXOVMQXMOU-OZIFAFRSSA-N
SMILES: O=C(O)C1=CC(C2CC2)=C3C(C)=C(C(F)=CN3C1=O)N4C[C@]([H])(CCCN5)[C@@]5([H])C4.Cl
Biological Activity: ABT-255 hydrochloride is an orally active anti-bacterial agent. ABT-255 hydrochloride exhibits potent in vitro potency (MIC = 0.016-0.031 μg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 hydrochloride shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 hydrochloride can be used for the study of pulmonary tuberculosis[1].
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ABT-255 hydrochloride | ABT-255 hydrochloride is an orally active anti-bacterial agent. ABT-255 hydrochloride exhibits potent in vitro potency (MIC = 0.016-0.031 μg/mL) against drug-susceptible and Rifampin (HY-B0272)- or Ethambutol (HY-B0535)-resistant Mycobacterium tuberculosis. ABT-255 hydrochloride shows efficacy against S. aureus, S. pneumoniae and E. coli and reduces viable counts of drug-resistant Mycobacterium tuberculosis in CF-1 mice. ABT-255 hydrochloride can be used for the study of pulmonary tuberculosis. | |||||||||||||||||||||
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