Psychotridine 

Psychotridine is a natural alkaloid isolated from Psychotria colorata, reveals an analgesic activity in nervous system and an inhibitory efficacy towards platelet aggregation^[1][2].

Psychotridine inhibits platelet aggregation induced by ADP, collagen and Thrombin through an interaction with cytoskeletal proteins, with IC₅₀s of 1.4, 1.4 and 3.9 μM, respectively^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Psychotridine (0-10 mg/kg, i.p., single dosage) exhibits in albiono CF-1 mice an analgesic activity in a dose-dependent manner towards pains induced by heat and capsaicin without motor deficits ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

863.15

C₅₅H₆₂N₁₀

52617-25-1

CN1[C@]2([H])[C@@](CC1)([C@]34C5=CC=CC([C@@]67C8=CC=CC=C8N[C@]6([H])N(CC7)C)=C5N[C@@]3([H])N(CC4)C)C9=CC=CC([C@@]%10%11C%12=CC=CC([C@@]%13%14C%15=CC=CC=C%15N[C@]%13([H])N(CC%14)C)=C%12N[C@]%10([H])N(CC%11)C)=C9N2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Amador TA, et al., Involvement of NMDA receptors in the analgesic properties of psychotridine. Phytomedicine. 2001 May;8(3):202-6.  [Content Brief]

  [2]. Beretz A, et al., Polyindolinic Alkaloids from Psychotria forsteriana. Potent Inhibitors of the Aggregation of Human Platelets. Planta Med. 1985 Aug;51(4):300-3.  [Content Brief]