1 Result for "

Cbl-b-IN-15

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cbl-b-IN-15" in MCE Product Catalog:

Cat. No.: HY-155477
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

Cbl-b-IN-15 (compound 25) is an inhibitor of the RING finger E3 ligase Cbl (IC50: 15 nM). Cbl-b refers to Casitas B-lineage lymphoma proto-oncogene-b, which inhibits T-cell, natural killer (NK) cell, and B-cell activation. Cbl-b-IN-15 activates T cell function with EC50=0.41 μM .
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