1 Result for "

Cdk1/2 Inhibitor III

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Cdk1/2 Inhibitor III" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-112462
CAS No.: 443798-55-8
Purity:  99.69%
Target:  

CDK

Research Areas:  

Cancer

Cdk1/2 Inhibitor III (compound 3n) is a highly potent and selective Cdk1/cyclin B and Cdk2/cyclin A inhibitor of with IC50s of 0.6 nM and 0.5 nM, respectively. Cdk1/2 Inhibitor III shows selectivity over VEGF-R2 (IC50 of 32 nM), GSK-3β (IC50 of 140 nM), and a other kinases. Cdk1/2 Inhibitor III inhibits in cell proliferation with IC50s of 20 nM, 35 nM and 92 nM for HCT-116, HeLa, and A375 cells, respectively .
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