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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Dioxins
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Dioxins" in MCE Product Catalog:
Category:
Alkaloids Monophenols Zygophyllaceae Peganum harmala Linn. Other Diseases Pyridine Alkaloids Phenols Plants Disease Research Fields
Target:
Cat. No.: HY-W762012
CAS No.: 3268-87-9
Synonyms: OCDD
Research Areas:
Octachlorodibenzo-p-dioxin (OCDD) is an environmental contaminant but is not acutely toxic. In rats, Octachlorodibenzo-p-dioxin (50 μg/kg i.v. or 50-5000 μg/kg p.o.) has a systemic elimination half-life of 3-5 months and accumulates and concentrates in the liver and adipose tissue after low-dose, repeated exposure. Repeated administration of octachlorodibenzo-p-dioxin causes increases in 7-ethoxyresorufin-O-deethylase (7-EROD) activity and total cytochrome P-450 levels .
Target:
Research Areas:
Diacetazotol inhibits dioxin-induced ethoxyresorufin-O-deethylase (EROD) activity with IC50 of 75±4 nM. Diacetazotol extracts from patent US20070032458, compound 3.
Cat. No.: HY-W762012S
CAS No.: 114423-97-1
Synonyms: OCDD-13C12
Cat. No.: HY-W094748S1
CAS No.: 125749-32-8
Cat. No.: HY-W748204
CAS No.: 109719-79-1
Cat. No.: HY-W762019
CAS No.: 39227-28-6
Synonyms: 1,2,3,4,7,8-HxCDD
Target:
Research Areas:
1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzo-p-dioxin (PCDD) congener. 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin can cause pale (fatty) livers, gastrointestinal hemorrhage and early death in H/W and line A rats at the highest dose (10,000 μg/kg). 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin also induces sinusoidal distension, and even severe peliosis in line B .
Cat. No.: HY-W748196S
CAS No.: 910107-83-4
Cat. No.: HY-169475
CAS No.: 19408-74-3
Synonyms: 1,2,3,7,8,9-HxCDD
Target:
Research Areas:
1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin (1,2,3,7,8,9-HxCDD) is a polychlorinated dibenzodioxin. 1,2,3,7,8,9-Hexachlorodibenzo-p-dioxin combined with 1,2,3,6,7,8-hexachlorodibenzo-p-dioxin induces the formation of liver adenomas or carcinomas in rats .
Cat. No.: HY-W727522
CAS No.: 40321-76-4
Synonyms: PCDD 54; 1,2,3,7,8-PeCDD
Target:
Research Areas:
1,2,3,7,8-Pentachlorodibenzo-p-dioxin is a biochemical reagent.
Cat. No.: HY-W762019S
CAS No.: 109719-80-4
Synonyms: 1,2,3,4,7,8-HxCDD-13C12
Cat. No.: HY-W715121S
CAS No.: 125749-35-1
Cat. No.: HY-W517076S
CAS No.: 109719-81-5
Cat. No.: HY-W715180S
CAS No.: 176761-26-5
Cat. No.: HY-N2625AR
CAS No.: 6028-07-5
Category:
Alkaloids Monophenols Zygophyllaceae Peganum harmala Linn. Pyridine Alkaloids Phenols Plants
Target:
Cat. No.: HY-W1006349
CAS No.: 67562-39-4
Synonyms: 1,2,3,4,6,7,8-HpCDF
Target:
Research Areas:
1,2,3,4,6,7,8-Heptachlorodibenzofuran (1,2,3,4,6,7,8-HpCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,4,6,7,8-Heptachlorodibenzofuran has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk .
Cat. No.: HY-W762018
CAS No.: 60851-34-5
Synonyms: 2,3,4,6,7,8-HxCDF
Target:
2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 2,3,4,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 0.687 and 0.575 nM, respectively) .
Cat. No.: HY-W762015
CAS No.: 57117-44-9
Synonyms: 1,2,3,6,7,8-HxCDF
Target:
Research Areas:
1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively). 1,2,3,6,7,8-Hexachlorodibenzofuran reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (EC50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively) .
Cat. No.: HY-W094748S
CAS No.: 69699-83-8
Cat. No.: HY-166949S
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
