1 Result for "

FXR agonist15

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "FXR agonist15" in MCE Product Catalog:

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Cat. No.: HY-179703
CAS No.: 2991276-14-1
Target:  

FXR

Research Areas:  

Inflammation/Immunology

FXR agonist 15 is a selective, potent and orally active farnesoid X receptor (FXR) agonist with EC50 of 0.76 μM. FXR agonist 15 exhibits no obvious activation on other nuclear receptors including LXRα/β, PXR, PPARα/β/γ, THR-β, with EC50 values all >10 μM. FXR agonist 15 can alleviate steatosis, lobular inflammation, hepatocyte ballooning and liver fibrosis. FXR agonist 15 can be used for the research of nonalcoholic steatohepatitis (NASH) .
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