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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Folinic acid
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Folinic acid" in MCE Product Catalog:
17
Category:
Human Gut Microbiota Metabolites Natural Products Plants Moraceae Endogenous metabolite Disease Research Fields Cancer Morus alba Linn.
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17
17 Publications Verification
Synonyms: Leucovorin calcium; Calcium folinate
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17
17 Publications Verification
Synonyms: Leucovorin calcium salt pentahydrate
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14
14 Cited Publications
Synonyms: Pirimecidan; Pirimetamin; RP 4753
Target:
Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
8
8 Cited Publications
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Research Areas:
5-Methyltetrahydrofolic acid disodium is the metabolite of Folinic acid (Leucovorin) (HY-17556). 5-Methyltetrahydrofolic acid disodium is involved in one-carbon metabolism and the transfer of methyl groups .
3
3 Cited Publications
Synonyms: Calcium levofolinate; CL307782
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Cat. No.: HY-127009
CAS No.: 68538-85-2
Synonyms: LevoFolinic acid; Levofolene
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Cat. No.: HY-17556S1
Synonyms: Leucovorin-d4 calcium hydrate
Cat. No.: HY-115429
CAS No.: 115940-48-2
Synonyms: (6R)-Leucovorin calcium; (6R)-Folinic acid calcium
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Research Areas:
Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity .
Cat. No.: HY-163828
CAS No.: 3035032-77-7
Research Areas:
PPA24 is a PP2A activator with a KD of 8.465 μM for PP2ACα. PPA24 induces cancer cell death via apoptosis. PP2ACα induces ROS generation and decreases the level of c-Myc expression. PPA24 can be used to study colorectal cancer (CRC), Folinic acid (HY-17556), 5-Fluorouracil (HY-90006), and Oxaliplatin (HY-17371) (FOLFOX)-resistant CRC, and melanoma cancer .
Synonyms: Pirimecidan (Standard); Pirimetamin (Standard); RP 4753 (Standard)
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Research Areas:
Pyrimethamine (Standard) is the analytical standard of Pyrimethamine. This product is intended for research and analytical applications. Pyrimethamine (Pirimecidan) is a potent, orally active dihydrofolate reductase (DHFR) inhibitor. Pyrimethamine is an antimalarial agent. Pyrimethamine affects the nucleoprotein metabolism of malarial parasites by interference in the folic–folinic acid systems and affects cell division by inhibiting the conversion of dihydrofolate to tetrahydrofolate .
Cat. No.: HY-17556A
CAS No.: 163254-40-8
Synonyms: Leucovorin disodium
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Synonyms: Leucovorin calcium (Standard); Calcium folinate (Standard)
Cat. No.: HY-W653912A
Cat. No.: HY-126733
CAS No.: 73951-54-9
Synonyms: (6R)-Folinic acid
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Research Areas:
(6R)-Leucovorin is a derivative of Folic Acid, a vitamin that plays a crucial role in DNA synthesis, DNA repair, and DNA methylation, and also serves as a cofactor in biological reactions involving folate .
Cat. No.: HY-17556B
CAS No.: 1097832-14-8
Synonyms: Leucovorin calcium hydrate
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Cat. No.: HY-155846
Antileishmanial agent-22 (compound 15b) is a parasite inhibitor and an antibacterial agent, with antileishmanial, antimalarial, and anti-tubercular activities. Antileishmanial agent-22 inhibits leishmanial (IC50=0.408 μM) based on antifolate mechanism. And, Antileishmanial agent-22 inhibits Folic acid and Folinic acid at 100 μM with inhibitory rates of 88% and 94%, respectively. Antileishmanial agent-22 inhibits P. berghei in vivo and in vitro, with 96.67% suppression under 48.4 μM/kg/day and 0.038 μM (IC50), respectively. Moreover, Antileishmanial agent-22 inhibits M. tuberculosis with MIC of 28.44 μM .
Cat. No.: HY-W654199
CAS No.: 2469007-14-3
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Research Areas:
5-Formyltetrahydropteroic acid hydrochloride is a derivative of Folinic acid (HY-17556).
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
