58-05-9
58-05-9
Chemical Structure
Folinic acid
Synonym(s): leucovorin
- CAS No.: 58-05-9
- Formula:C20H23N7O7
- Molecular Weight:473.44
IUPAC Name: (4-(((2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid
InChIKey: VVIAGPKUTFNRDU-ABLWVSNPSA-N
SMILES: O=C(O)CC[C@@H](C(O)=O)NC(C1=CC=C(NCC2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O
Biological Activity: Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Folinic acid | 99.98% | Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Folinic acid (Standard) | 98.21% | Folinic acid (Standard) is the analytical standard of Folinic acid. This product is intended for research and analytical applications. Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease MTX-induced toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Folinic acid-d4 calcium hydrate | 91.69% | Folinic acid-d4-1 (Leucovorin-d4-1) calcium hydrate is deuterated labeled Folinic acid (HY-17556). Folinic acid (Leucovorin) is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Methyltetrahydrofolic acid (Standard) | 98.58% | 5-Methyltetrahydrofolic acid (Standard) (5-Methyl THF (Standard)) is the analytical standard of 5-Methyltetrahydrofolic acid (HY-113046). This product is intended for research and analytical applications. 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
5-Methyltetrahydrofolic acid-13C6 | 5-Methyltetrahydrofolic acid-13C6 (5-Methyl THF-13C6) is 13C labeled 5-Methyltetrahydrofolic acid. 5-Methyltetrahydrofolic acid (5-Methyl THF) is the main circulating form of folic acid in the body and is involved in a variety of biochemical reactions. 5-Methyltetrahydrofolic acid regulates cardiovascular function by increasing the production of endothelin-1 (ET-1) in low-density lipoprotein-treated endothelial cells and can be used in the study of cardiovascular diseases. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Calcium dextrofolinate | 95.33% | Calcium dextrofolinate is a stereoisomer of Calcium folinate. Calcium folinate (Folinic acid calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(6R)-Leucovorin | (6R)-Leucovorin is a derivative of Folic Acid, a vitamin that plays a crucial role in DNA synthesis, DNA repair, and DNA methylation, and also serves as a cofactor in biological reactions involving folate. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Levoleucovorin | 98.53% | Levoleucovorin (Levofolinic acid; Levofolene) is the pharmacologically and orally active levoisomer of Folinic acid (HY-17556), a synthetic folate analogue. Levoleucovorin can inhibit LOXL2 with an IC50 of 68.81 μM. Levoleucovorin can inhibit cancer cells proliferation, migration and induce apoptosis. Levoleucovorin can be used as a rescue agent for high-dose Methotrexate (HY-14519). Levoleucovorin can reduce the frequency of embryonic malformations. Levoleucovorin can be used for the research of can and endocrinology, such as breast cancer and osteosarcoma. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Folinic acid calcium (Standard) | ≥98% | Folinic acid (calcium) (Standard) is the analytical standard of Folinic acid (calcium). This product is intended for research and analytical applications. Folinic acid calcium (Leucovorin calcium) is a biological folic acid and is generally administered along with methotrexate (MTX) as a rescue agent to decrease MTX-induced toxicity. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Levomefolic acid | 99.59% | Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Levomefolic acid-13C,d3 | 98.93% | Levomefolic acid-13C,d3 is the deuterium labeled Levomefolic acid (HY-14781). Levomefolic acid (5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Levomefolic acid-13C5 | Levomefolic acid-13C5 is the 13C labeled Levomefolic acid. Levomefolic acid (L-5-MTHF) is an orally active, brain-penetrant natural active form of folic acid and is one of the most widely used folic acid food supplements. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Folinic acid calcium hydrate | Folinic acid (Leucovorin) calcium hydrate is a biological folic acid and is generally administered along with Methotrexate (HY-14519) as a rescue agent to decrease Methotrexate-induced toxicity. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
