1 Result for "

GBR401

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GBR401" in MCE Product Catalog:

Cat. No.: HY-P991542
CAS No.: 1931954-95-8

Target:  

CD19

Research Areas:  

Cancer

GBR-401 is a humanized anti-CD19 monoclonal antibody with high affinity for FcγRIIIa. GBR-401 exerts a potent in vitro and in vivo cytotoxic activity against various B-cell malignancies. GBR-401 induces cell death by antibody dependent cellular cytotoxicity (ADCC) and direct killing effect. GBR-401 demonstrates potent activity of depleting malignant B cells and prolongs mice survival in multiple xenograft severe combined immunodeficiency (SCID) mice models .
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