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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
GIPR/GLP-1R agonist
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "GIPR/GLP-1R agonist" in MCE Product Catalog:
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Cat. No.: HY-164535
CAS No.: 2887445-76-1
Synonyms: AMG 133
Cat. No.: HY-P10736
CAS No.: 3137854-22-6
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AMG133 peptide payload is a GLP-1 analog agonist peptide. AMG133 peptide potently activates GLP-1R, and exhibits weight loss and metabolic improvement activities. AMG133 peptide payload can be used for the synthesis of AMG 133 (HY-164535) .
Cat. No.: HY-P10302A
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Cat. No.: HY-P10031
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Cat. No.: HY-P10302
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Cat. No.: HY-P11237
CAS No.: 2869147-44-2
Synonyms: CT-388
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Cat. No.: HY-P10031A
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Cat. No.: HY-173479
CAS No.: 3108380-54-4
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GLP-1R agonist 30 is a selective and orally active GLP-1R agonist with an EC50 of 0.048 nM. GLP-1R has excellent selectivity, with EC50 greater than 20 μM for GLP-2R, GIPR, and GCPR. GLP-1R agonist significantly increases cAMP-stimulating activity while markedly reducing hERG inhibitory activities. GLP-1R agonist has preferable absorption and excellent β-arrestin pathway selectivity. GLP-1R agonist effectively improves glucose tolerance and promoted insulin secretion in B-hGLP1R knock-in mice .
Cat. No.: HY-P3506CP
CAS No.: 2381089-83-2
Synonyms: LY3437943 (crude)
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Cat. No.: HY-P11818
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Cat. No.: HY-171302
CAS No.: 2766799-78-2
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GLP-1R/GIPR agonist-2 is a GIPR agonist. GLP-1R/GIPR agonist-2 potentiates GIP(1-42)-induced intracellular cAMP production in cells expressing human GIPR. GLP-1R/GIPR agonist-2 can be used for the research of type II diabetes mellitus .
Cat. No.: HY-P11279
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Cat. No.: HY-P11275
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Cat. No.: HY-P12137
CAS No.: 2869056-74-4
Synonyms: RAY1225
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Bilpatide (RAY1225) is a dual agonist of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR). Bilpatide is applicable to research related to obesity and diabetes .
Cat. No.: HY-P11487
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Cat. No.: HY-181709
Synonyms: TG062
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TPM003 (TG062) is a triple agonist of GLP-1R, GIPR and GCGR, with EC50 values of 33.9, 12.5 and 92.9 pM, respectively. TPM003 suppresses appetite, regulates blood glucose, enhances insulin sensitivity, reduces gastrointestinal intolerance, promotes hepatic lipid mobilization and increases energy expenditure. TPM003 induces weight loss, improves metabolic parameters, reverses hepatic steatosis and optimizes liver function markers. TPM003 is applicable for research on obesity and non-alcoholic steatohepatitis .
Cat. No.: HY-P11672
CAS No.: 3058127-20-8
Synonyms: HDM1005
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
