2. GPCR/G Protein
  3. GLP Receptor
  4. Poterepatide

Poterepatide (HDM1005) is a long-acting GLP-1R/GIPR peptide dual agonist. Poterepatide exhibits potent activity on both GLP-1 and GIP receptors. Poterepatide can be used for the study of obesity and type 2 diabetes.

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Custom Peptide Synthesis

Poterepatide

Poterepatide Chemical Structure

CAS No. : 3058127-20-8

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Poterepatide Related Antibodies

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Description

Poterepatide (HDM1005) is a long-acting GLP-1R/GIPR peptide dual agonist. Poterepatide exhibits potent activity on both GLP-1 and GIP receptors. Poterepatide can be used for the study of obesity and type 2 diabetes[1].

Clinical Trial
Molecular Weight

5199.94

Formula

C243H382N52O73
CAS No.
Sequence

Tyr-{Aib}-Glu-Gly-Thr-{Phe(αMe)}-Thr-Ser-Asp-Tyr-{Aib}-Ile-{Aib}-Leu-Asp-Lys-Gln-Ala-Gln-Ala-Glu-Phe-Val-{K(AEEA-AEEA-AEEA-{γGlu}-C22 diacid)}-Trp-Leu-Leu-Lys-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Lys-NH2
Sequence Shortening

Y-{Aib}-EGT-{Phe(αMe)}-TSDY-{Aib}-I-{Aib}-LDKQAQAEFV-{K(AEEA-AEEA-AEEA-{γGlu}-C22 diacid)}-WLLKGGPSSGAPPPSK-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Poterepatide Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Poterepatide3058127-20-8HDM1005HDM 1005HDM-1005GLP ReceptorGLP-1R/GIPR agonistobesitytype 2 diabetesInhibitorinhibitorinhibit

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