2. GPCR/G Protein
  3. GLP Receptor
  4. GLP-1R/GIPR agonist-2

GLP-1R/GIPR agonist-2 is a GIPR agonist. GLP-1R/GIPR agonist-2 potentiates GIP(1-42)-induced intracellular cAMP production in cells expressing human GIPR. GLP-1R/GIPR agonist-2 can be used for the research of type II diabetes mellitus.

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GLP-1R/GIPR agonist-2

GLP-1R/GIPR agonist-2 Estructura química

No. CAS : 2766799-78-2

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GLP-1R/GIPR agonist-2 Related Antibodies

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Descripciòn

GLP-1R/GIPR agonist-2 is a GIPR agonist. GLP-1R/GIPR agonist-2 potentiates GIP(1-42)-induced intracellular cAMP production in cells expressing human GIPR. GLP-1R/GIPR agonist-2 can be used for the research of type II diabetes mellitus[1].

In Vitro

GLP-1R/GIPR agonist-2 (Example 1) (30 min) acts as a positive allosteric modulator of the human GIPR in HEK293 cells, with an EC50 of 11.9 nM and maximal potentiation equivalent to 101% of the positive control response[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GLP-1R/GIPR agonist-2 Related Antibodies
Peso molecular

577.60

Fòrmula

C32H43Cl2FN2O2
No. CAS
SMILES

COC1=CC=C([C@H](N(CC2)C(C3=CC=C(C=C3)C(C)C)C)C)C2=C1C4=CC(NCC(C)C)=C(C(F)=C4)O.Cl.Cl
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Room temperature in continental US; may vary elsewhere.
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GLP-1R/GIPR agonist-2 Related Classifications

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Keywords:

GLP-1R/GIPR agonist-22766799-78-2GLP Receptortype II diabetes mellitusglucose-dependent insulinotropic polypeptide receptorhuman GIPRpositive allosteric modulatorhuman GIP receptorintracellular cAMPHEK293 cellsInhibitorinhibitorinhibit

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Nombre del producto:
GLP-1R/GIPR agonist-2
Cat. No.:
HY-171302
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