1 Result for "

GLI1-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GLI1-IN-3" in MCE Product Catalog:

Cat. No.: HY-172449
Target:  

Hedgehog

Research Areas:  

Cancer

GLI1-IN-3 (Compound 11a), a triterpenoid analogue, can inhibit Hedgehog signaling in GLI1 overexpression cancer cells. GLI1-IN-3 inhibits the proliferation in NSCLC and prostate cancer cell lines exhibiting hyper-activated Hh signaling. GLI1-IN-3 can also decrease the expression of endogenous GLI1 protein and its target genes associated with tumor progression and proliferation in A549 and DU-145 cancer cells .
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