1 Result for "

GM47-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "GM47-1" in MCE Product Catalog:

Cat. No.: HY-179593
Target:  

Bacterial

Research Areas:  

Inflammation/Immunology

GM47-1, a naphthalene scaffold derivative, is a potent mycolic acid transporter MmpL3 inhibitor exhibiting potent bactericidal activity against Mycobacterium abscessus (Mabs) with an MIC50 of 2.1 µM. GM47-1 targets MmpL3, disrupts cell wall integrity, and induces ATP leakage and uncouples respiration. GM47-1 can be used for Mycobacterium abscessus pulmonary disease (Mabs-PD) research .
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