95 Results for "

GnRH

" in MedChemExpress (MCE) Product Catalog:
Products (95)

95 Results for "GnRH" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-16168A
CAS No.: 214766-78-6
Synonyms: FE 200486 free base
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology Cancer

Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM). Degarelix acetate Degarelix acetate (FE 200486) is used for the research of prostate cancer .
loading...
    loading...
11
11 Publications Verification
Cat. No.: HY-16168
CAS No.: 934016-19-0
Synonyms: FE 200486
Target:  

GnRH Receptor

Research Areas:  

Cancer

Degarelix acetate (FE 200486) is a decapeptide that shows high affinity/selectivity to human gonadotropin-releasing hormone (GnRH) receptor (IC50 = 3 nM). Degarelix acetate (FE 200486) is used for the research of prostate cancer .
loading...
    loading...
4
4 Cited Publications
Cat. No.: HY-P2161B
Target:  

Kisspeptin Receptor

Research Areas:  

Cancer

TAK-683 acetate is a potent full KISS1 receptor (KISS1R) agonist (IC50=170 pM) with improved metabolic stability. TAK-683 acetate is a nonapeptide metastin analog, exhibits agonistic activities to KISS1R with EC50 values of 0.96 nM and 1.6 nM for human and rat, respectively . TAK-683 acetate depletes GnRH in the hypothalamus and reduces plasma FSH, LH, and testosterone levels in vivo, it has the potential for the study of hormone-dependent prostate cancer .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-13673A
CAS No.: 145781-92-6
Purity:  99.92%
Synonyms: ICI-118630 acetate
Target:  

GnRH Receptor Apoptosis

Research Areas:  

Endocrinology Cancer

Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-P0051
CAS No.: 61012-19-9
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Lecirelin, a synthetic gonadotropin-releasing hormone (GnRH) analogue, acts as a GnRH agonist. Lecirelin is widely used for the research of bovine ovarian follicular cysts .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-16474
CAS No.: 737789-87-6
Synonyms: TAK-385
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Relugolix (TAK-385)?is a potent, orally active, nonpeptidic gonadotropin-releasing hormone (GnRH) antagonist. Relugolix possesses high affinity and potent antagonistic activity for human receptor (binding IC50=0.33 nM) and monkey receptor (IC50=0.32 nM) compared with TAK-013 (HY-100209) . Relugolix is used for the study of sex-hormone-dependent diseases, such as including endometriosis, uterine fibroids and prostate cancer et al .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-14369
CAS No.: 832720-36-2
Purity:  99.94%
Synonyms: NBI-56418 sodium
Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-17405
CAS No.: 79561-22-1
Synonyms: Alarelin
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

Alarelin acetate is a synthetic GnRH agonist.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-14789
CAS No.: 834153-87-6
Purity:  96.22%
Synonyms: NBI-56418
Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-13534
CAS No.: 183552-38-7
Purity:  99.90%
Synonyms: R3827; PPI 149
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Abarelix (R3827; PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer treatment.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P0048
CAS No.: 52435-06-0
Synonyms: Surfagon
Target:  

GnRH Receptor

Research Areas:  

Others

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (Surfagon, Mwt 1167.34 Da) is an agonist of gonadotropin-releasing hormone (GnRH). (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH can be used as an internal standard for the LC-MS analysis of leuprorelide acetate. (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH has potential applications in biochemical analysis and fertility .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1428
CAS No.: 311309-25-8
Research Areas:  

Endocrinology

RFRP-1(human) is a gonadotropin-inhibitory hormone (GnIH) homolog. RFRP-1(human) targets human gonadotropin-releasing hormone (GnRH) neurons and gonadotropes and potently inhibits gonadotropin. RFRP-1(human) is a potent Neuropeptide FF (NPFF) receptor agonist with EC50s of 0.0011 nM and 29 nM for NPFF2 and NPFF1, respectively .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P3641A
Target:  

GnRH Receptor

Kisspeptin 13 TFA is the TFA salt form of Kisspeptin 13 (HY-P3641). Kisspeptin-13 TFA inhibits glucose-induced insulin secretion with an IC50 of 1.2 nM. Kisspeptin 13 TFA activates the hypothalamic-pituitary-adrenal (HPA) axis, causes hyperthermia, motor behavior and anxiety in rats. Kisspeptin 13 TFA interacts with α2-adrenergic and 5-HT2 serotonin receptors, exhibits antidepressant efficacy. Kisspeptin 13 TFA is an activator for GPR54 and GnRH receptor, which enhances memory and can be used in Alzheimer's disease research .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-13534A
CAS No.: 547741-72-0
Purity:  99.89%
Synonyms: PPI 149 Acetate; R 3827 Acetate
Target:  

GnRH Receptor

Research Areas:  

Endocrinology Cancer

Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research .
loading...
    loading...
Cat. No.: HY-P3582
CAS No.: 96497-82-4
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .
loading...
    loading...
Cat. No.: HY-P0242
CAS No.: 86933-75-7
Neurokinin B is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B can be used in studies related to hypogonadotropic hypogonadism .
loading...
    loading...
Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Neurokinin B TFA is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B TFA preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B TFA regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B TFA exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B TFA can be used in studies related to hypogonadotropic hypogonadism .
loading...
    loading...
Cat. No.: HY-P0243
CAS No.: 86073-88-3
Synonyms: Salmon GnRH; Salmon gonadotropin-releasing hormone; sGnRH
Target:  

GnRH Receptor

Research Areas:  

Metabolic Disease

Luteinizing Hormone Releasing Hormone (LH-RH), salmon (Salmon GnRH) is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.
loading...
    loading...
Cat. No.: HY-P1628
CAS No.: 124904-93-4
Target:  

GnRH Receptor

Research Areas:  

Metabolic Disease

Ganirelix is a competitive and selective gonadotropin releasing hormone (GnRH) antagonist. Ganirelix prevents endogenous GnRH from inducing luteinising hormone (LH) and follicle stimulating hormone relea .
loading...
    loading...
Cat. No.: HY-P0053
CAS No.: 38234-21-8
Target:  

GnRH Receptor

Research Areas:  

Endocrinology

Fertirelin is a GnRH and LH-RH analogue. Fertirelin can be used of the study for reversing cow follicular cysts .
loading...
    loading...