2. GPCR/G Protein
  3. GnRH Receptor
  4. Abarelix Acetate

Abarelix Acetate  (Synonyms: PPI 149 Acetate; R 3827 Acetate)

Cat. No.: HY-13534A Purity: 99.90%
COA Handling Instructions

Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Abarelix Acetate Chemical Structure

Abarelix Acetate Chemical Structure

CAS No. : 547741-72-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 487 In-stock
Solution
10 mM * 1 mL in DMSO USD 487 In-stock
Solid
5 mg USD 180 In-stock
10 mg USD 300 In-stock
25 mg USD 660 In-stock
50 mg USD 1140 In-stock
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Abarelix Acetate:

Abarelix Acetate Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Abarelix Acetate

WB

    Abarelix Acetate purchased from MedChemExpress. Usage Cited in: Am J Physiol Endocrinol Metab. 2020 Jul 1;319(1):E81-E90.  [Abstract]

    EPHA7, ERα, and ERβ protein expression in the hypothalamus of abarelix-treated rats injected with EPHA7-Fc.

    • Biological Activity

    • Purity & Documentation

    • References

    • Customer Review

    Description

    Abarelix Acetate (PPI 149 Acetate; R 3827 Acetate) is a potent gonadotrophin-releasing hormone (GnRH) antagonist, used for prostate cancer research[1].

    IC50 & Target

    GnRH[1]
    Clinical Trial
    Molecular Weight

    1476.12

    Appearance

    Solid

    Formula

    C74H99ClN14O16
    CAS No.
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Sealed storage, away from moisture

    Powder -80°C 2 years
    -20°C 1 year

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 100 mg/mL (67.75 mM)

    H2O : 25 mg/mL (16.94 mM; Need ultrasonic)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 0.6775 mL 3.3873 mL 6.7745 mL
    5 mM 0.1355 mL 0.6775 mL 1.3549 mL
    10 mM 0.0677 mL 0.3387 mL 0.6775 mL
    *Please refer to the solubility information to select the appropriate solvent.
    In Vivo:
    • 1.

      Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

      Solubility: ≥ 2.5 mg/mL (1.69 mM); Clear solution

    • 2.

      Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

      Solubility: ≥ 2.5 mg/mL (1.69 mM); Clear solution

    • 3.

      Add each solvent one by one:  10% DMSO    90% Corn Oil

      Solubility: ≥ 2.5 mg/mL (1.69 mM); Clear solution

    *All of the co-solvents are available by MedChemExpress (MCE).
    Purity & Documentation

    Purity: 99.90%

    COA (252 KB) LCMS (267 KB)

    Handling Instructions (2659 KB)
    References
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    • If you have published this work, please enter the PubMed ID.
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    Abarelix Acetate Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
    = × ×

    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

    Keywords:

    Abarelix547741-72-0PPI 149R 3827PPI149PPI-149R3827R-3827GnRH ReceptorGonadotropin releasing hormone receptorGNRHRInhibitorinhibitorinhibit

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