1 Result for "

HDAC/HSP90-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDAC/HSP90-IN-4" in MCE Product Catalog:

Cat. No.: HY-146212
Target:  

HDAC HSP

Research Areas:  

Cancer

These compounds have strong hdac and hsp90 inhibitory activities. Compound 20 (HDAC ic50   =   194   nm; Hsp90 α < b> Ic50 =   153   nm) and compound 26 ((HDAC ic50=   360   nm; Hsp90 α < b> Ic50   =   77   nm) shows the strongest HDAC and HSP90 α Inhibitory activity. Both compounds can induce hsp90 expression and down regulate hsp90 client proteins, which play an important role in regulating the survival and invasion of cancer cells.
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