1 Result for "

HDAC1-IN-5

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HDAC1-IN-5" in MCE Product Catalog:

Cat. No.: HY-151153
Research Areas:  

Cancer

HDAC1-IN-5 is a potent HDAC1 inhibitor with IC50 values of 15 nM and 20 nM for HDAC1 and HDAC6, respectively. HDAC1-IN-5 can enhance the acetylation of histone H3 and α-tubulin, as well as promote the activation of caspase 3 in cancer cells, thereby inducing apoptosis. HDAC1-IN-5 induces chromatin damage by binding with DNA. HDAC1-IN-5 has strong inhibitory activity against tumor growth in xenograft mice .
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