4 Results for "

Hecogenin acetate

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Hecogenin acetate" in MCE Product Catalog:

Hecogenin acetate
Hecogenin acetate
0 Images
Cat. No.: HY-126941
CAS No.: 915-35-5
Purity:  99.30%
Category:  

Agave americana Linn. Agavaceae Plants Steroids

Target:  

ERK MMP Reactive Oxygen Species (ROS) NF-κB p38 MAPK NOD-like Receptor (NLR) TRP Channel TNF Receptor Interleukin Related

Hecogenin acetate is an orally active steroid saponin aglycone with extensive biological activities. Hecogenin acetate inhibits the phosphorylation of NF-κB and p38 MAPK signaling pathways, antagonizes TRPA1/TRPM8 channels, inhibits the production of pro-inflammatory cytokines, and has anti-inflammatory and analgesic effects. Hecogenin acetate inhibits the production of ROS and the activation of NLRP3 inflammasome; downregulates the expression of MMP-2, and has neuroprotective and anti-tumor activities. Hecogenin acetate enhances gastric mucosal defense and promotes ulcer healing. Hecogenin acetate can be used in combination with certain antibiotics to regulate bacterial efflux pumps and restore antibiotic sensitivity .
loading...
    loading...
View All Sizes
1
Hecogenin
Hecogenin
0 Images
1 Cited Publications
Cat. No.: HY-N1422
CAS No.: 467-55-0
Category:  

Agavaceae Plants Agave sisalana Perr. ex Engelm. Disease Research Fields Inflammation/Immunology Steroids

Target:  

Fungal

Hecogenin is a steroid saponin isolated from Agave sisalana and is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and gastroprotective effects .
loading...
    loading...
View All Sizes
Hecogenin (Standard)
Hecogenin (Standard)
0 Images
Cat. No.: HY-N1422R
CAS No.: 467-55-0
Category:  

Agavaceae Plants Agave sisalana Perr. ex Engelm. Steroids

Target:  

Reference Standards Fungal

Hecogenin (Standard) is the analytical standard of Hecogenin. This product is intended for research and analytical applications. Hecogenin is a steroid saponin isolated from Agave sisalana and is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and gastroprotective effects .
loading...
    loading...
View All Sizes
(25R)-12α-Hydroxyspirost-4-en-3-one
(25R)-12α-Hydroxyspirost-4-en-3-one
0 Images
Cat. No.: HY-N11485
CAS No.: 50888-50-1
Category:  

Triterpenes Terpenoids Endogenous metabolite

Target:  

Drug Metabolite

(25R)-12α-Hydroxyspirost-4-en-3-one is a minor metabolite produced by the action of Nocardia globerula on Hecogenin (HY-N1422) .
loading...
    loading...
View All Sizes
Assay Types