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Results for "

Hexose

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

2

Biochemical Assay Reagents

7

Natural
Products

9

Isotope-Labeled Compounds

2

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13966
    2-Deoxy-D-glucose
    340+ Cited Publications

    2-DG; 2-Deoxy-D-arabino-Hexose; D-Arabino-2-deoxyHexose

    		 Hexokinase HSV Apoptosis Cancer
    2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
    2-Deoxy-D-glucose
  • HY-10617A
    Rucaparib
    45+ Cited Publications

    AG014699; PF-01367338

    		 PARP Cancer
    Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib
  • HY-N1480
    (-)-Fucose

    6-Desoxygalactose; L-(-)-Fucose; L-Galactomethylose

    		 Endogenous Metabolite Parasite Infection Metabolic Disease Cancer
    (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .
    (-)-Fucose
  • HY-10617
    Rucaparib phosphate
    45+ Cited Publications

    AG-014699 phosphate; PF-01367338 phosphate

    		 PARP Cancer
    Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib phosphate
  • HY-102003
    Rucaparib monocamsylate
    35+ Cited Publications

    AG014699 monocamsylate; PF-01367338 monocamsylate

    		 PARP Cancer
    Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib monocamsylate
  • HY-148315
    GLUT1-IN-2

    		GLUT Infection
    GLUT1-IN-2 (compound 17) is a GLUT1 inhibitor with an IC50 value of 12 μM. GLUT1-IN-2 shows inhibitory effect to Plasmodium falciparum hexose transporter PfHT with an IC50 value of 13 μM. GLUT1-IN-2 can be used for the research of infection .
    GLUT1-IN-2
  • HY-13966S
    2-Deoxy-D-glucose-d1
    1 Publications Verification

    2-DG-d1; 2-Deoxy-D-arabino-Hexose-d1; D-Arabino-2-deoxyHexose-d1

    		 Isotope-Labeled Compounds Apoptosis Hexokinase HSV Cancer
    2-Deoxy-D-glucose-d is the deuterium labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
    2-Deoxy-D-glucose-d1
  • HY-13966S2
    2-Deoxy-D-glucose-13C

    2-DG-13C; 2-Deoxy-D-arabino-Hexose-13C; D-Arabino-2-deoxyHexose-13C

    		 Isotope-Labeled Compounds Apoptosis Hexokinase HSV Cancer
    2-Deoxy-D-glucose- 13C is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
    2-Deoxy-D-glucose-13C
  • HY-17656
    C3361

    		Parasite Infection
    C3361 is a moderate specific Plasmodium falciparum hexose transporter 1 (PfHT1) and Plasmodium berghei hexose transporter 1 (PbHT1) inhibitor with Ki values of 8.6 and 9.4 μM. C3361 inhibits TgGT1 with a Ki of 82 μM. C3361 attenuates hepatic (IC50 = 15 μM) and ookinete development of P. berghei. C3361 can suppress the growth of blood-stage parasites. C3361 can be used for the research of infection, such as malaria .
    C3361
  • HY-P2761
    Glucokinase

    		Biochemical Assay Reagents Metabolic Disease
    Glucokinase is a glucose-phosphorylating enzyme that has an important role in glucose homeostasis. Glucokinase acts as a glucose sensot of pancreatic β-cells. Glucokinase regulates the conversion of glucose to glucogen as well as gluconeogenesis. Glucokinase in mammals can phosphorylate hexoses like mannose or fructose in addition to glucose. Glucokinase can be studied in research on diabetes .
    Glucokinase
  • HY-102003A
    Rucaparib camsylate

    AG014699 camsylate; PF-01367338 camsylate

    		 PARP Cancer
    Rucaparib (AG014699) camsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib camsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib camsylate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib camsylate
  • HY-E70010
    Aldose 1-epimerase

    mutarotases

    		 Endogenous Metabolite Others
    Aldose 1-epimerase (mutarotases) is a key enzyme of carbohydrate metabolism catalysing the interconversion of the α- and β-anomers of hexose sugars such as glucose and galactose. Aldose 1-epimerase is essential for normal carbohydrate metabolism and the production of complex oligosaccharides .
    Aldose 1-epimerase
  • HY-W039923
    β-D-Galactose pentaacetate

    		Insulin Receptor Endocrinology
    β-D-Galactose pentaacetate is a negative regulator of insulin with plasma membrane penetrating ability and can be hydrolyzed by intracellular esterases. β-D-Galactose pentaacetate inhibits Leucine (HY-N0486)-induced insulin release in Wistar rat islets, potentially preventing excessive insulin release in pathological conditions .
    β-D-Galactose pentaacetate
  • HY-176834
    3-Deoxy-3-fluoro-D-fructose

    		GLUT Cancer
    3-Deoxy-3-fluoro-D-fructose (Compound 12) is a derivative of 2,5-Anhydro-D-mannitol. 3-Deoxy-3-fluoro-D-fructose is a selective probe of Hexose transporter 5 (GLUT5). 3-Deoxy-3-fluoro-D-fructose inhibits the transport of D-fructose labeled with 14C by GLUT5 with IC50s of 1.16 and 2.37 µM in EMT-6 and MCF-7 cells. 3-Deoxy-3-fluoro-D-fructose can be used for positron emission tomography (PET) imaging of cancers .
    3-Deoxy-3-fluoro-D-fructose
  • HY-10617B
    Rucaparib hydrochloride

    AG014699 hydrochloride; PF-01367338 hydrochloride

    		 PARP Cancer
    Rucaparib (AG014699) hydrochloride is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib hydrochloride is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib hydrochloride has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib hydrochloride
  • HY-10617C
    Rucaparib tartrate

    AG-014699 tartrate; PF-01367338 tartrate

    		 PARP Cancer
    Rucaparib (AG014699) tartrate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib tartrate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib tartrate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib tartrate
  • HY-10617AR
    Rucaparib (Standard)

    AG014699 (Standard); PF-01367338 (Standard)

    		 Reference Standards PARP Cancer
    Rucaparib (Standard) is the analytical standard of Rucaparib. This product is intended for research and analytical applications. Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib (Standard)
  • HY-N1480S1
    (-)-Fucose-13C-1

    6-Desoxygalactose-13C-1; L-(-)-Fucose-13C-1; L-Galactomethylose-13C-1

    		 Isotope-Labeled Compounds Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose- 13C-1 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
    (-)-Fucose-13C-1
  • HY-N1480R
    (-)-Fucose (Standard)

    6-Desoxygalactose (Standard); L-(-)-Fucose (Standard); L-Galactomethylose (Standard)

    		 Reference Standards Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose (Standard) is the analytical standard of (-)-Fucose. This product is intended for research and analytical applications. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions. (-)-Fucose is orally active, inhibits CL11-induced inflammatory response in kidney and tumor growth .
    (-)-Fucose (Standard)
  • HY-153612
    MMV009085

    		GLUT Parasite Infection Inflammation/Immunology
    MMV009085 is a potent PfHT1 (Plasmodium falciparum hexose transporter)-specific inhibitor and a potential anti-malarial agent . MMV009085 is also a human glucose transporter inhibitor, it has high potency in inhibiting both glucose uptake (IC50: 2.6 μM in glucose uptake assay) and growth of the parasites (EC50: 1.23±0.04 μM against 3D7) .
    MMV009085
  • HY-13966S4
    2-Deoxy-D-glucose-13C-1

    2-DG-13C-1; 2-Deoxy-D-arabino-Hexose-13C-1; D-Arabino-2-deoxyHexose-13C-1

    		 Isotope-Labeled Compounds Apoptosis Hexokinase HSV Cancer
    2-Deoxy-D-glucose- 13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
    2-Deoxy-D-glucose-13C-1
  • HY-13966S3
    2-Deoxy-D-glucose-13C6

    2-DG-13C6; 2-Deoxy-D-arabino-Hexose-13C6; D-Arabino-2-deoxyHexose-13C6

    		 Isotope-Labeled Compounds Apoptosis Hexokinase HSV Cancer
    2-Deoxy-D-glucose- 13C6 (2-DG- 13C6) is 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase .
    2-Deoxy-D-glucose-13C6
  • HY-12956B
    (5R)-Dinoprost

    Prostaglandin F2β; PGF2β

    		 Endogenous Metabolite Others
    (5R)-Dinoprost is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. (5R)-Dinoprost (Prostaglandin F2β) induces dose-dependent release of hexose containing mucin .
    (5R)-Dinoprost
  • HY-125396
    11-Deoxyprostaglandin F2β

    11-Deoxy-PGF2β

    		 Endogenous Metabolite Others
    11-Deoxyprostaglandin F2β (11-deoxy PGF2β) is an analog of PGF2β (HY-12956B). PGF2β is a metabolite produced by cyclooxygenase metabolism of arachidonic acid. PGF2β induces dose-dependent release of hexose containing mucin .
    11-Deoxyprostaglandin F2β
  • HY-10617D
    Rucaparib acetate

    AG014699 acetate; PF-01367338 acetate

    		 PARP Cancer
    Rucaparib (AG014699) acetate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib acetate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib acetate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib acetate
  • HY-10617R
    Rucaparib phosphate (Standard)

    AG-014699 phosphate (Standard); PF-01367338 phosphate (Standard)

    		 Reference Standards PARP Cancer
    Rucaparib (phosphate) (Standard) is the analytical standard of Rucaparib (phosphate). This product is intended for research and analytical applications. Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib phosphate (Standard)
  • HY-10617AS
    Rucaparib-d8

    AG014699-d8 ; PF-01367338-d8

    		 Isotope-Labeled Compounds PARP Cancer
    Rucaparib-d8 (AG014699-d8 ) is deuterium labeled Rucaparib. Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib-d8
  • HY-N1480S
    (-)-Fucose-13C

    6-Desoxygalactose-13C; L-(-)-Fucose-13C; L-Galactomethylose-13C

    		 Isotope-Labeled Compounds Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose- 13C is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti
    (-)-Fucose-13C
  • HY-114850A
    (5R)-Dinoprost tromethamine

    Prostaglandin F2β tromethamine; PGF2β tromethamine

    		 Endogenous Metabolite Others
    (5R)-Dinoprost tromethamine (Prostaglandin F2β tromethamine) is a metabolite produced by the metabolism of arachidonic acid cyclooxygenase. (5R)-Dinoprost tromethamine induces dose-dependent release of hexosaccharide containing mucin .
    (5R)-Dinoprost tromethamine
  • HY-N1480S2
    (-)-Fucose-13C-2

    6-Desoxygalactose-13C-2; L-(-)-Fucose-13C-2; L-Galactomethylose-13C-2

    		 Isotope-Labeled Compounds Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose- 13C-2 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
    (-)-Fucose-13C-2
  • HY-N1480S3
    (-)-Fucose-13C-3

    6-Desoxygalactose-13C-3; L-(-)-Fucose-13C-3; L-Galactomethylose-13C-3

    		 Isotope-Labeled Compounds Endogenous Metabolite Parasite Infection Metabolic Disease
    (-)-Fucose- 13C-3 is the 13C labeled (-)-Fucose. (-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interacti[
    (-)-Fucose-13C-3
  • HY-128394R
    L-Gulose (Standard)

    		Reference Standards Drug Intermediate Others
    L-Gulose (Standard) is the analytical standard substance of L-Gulose. This product is used for research and analytical applications. L-Gulose is a rare L-type hexose sugar found in nature and is a key structural unit for synthesizing various important active compounds (such as vitamin C).
    L-Gulose (Standard)
  • HY-W416153
    2-Deoxy-D-arabino-hexose propylene dithioacetal

    		Biochemical Assay Reagents Others
    THP-NCS is a biochemical assay reagent.
    2-Deoxy-D-arabino-hexose propylene dithioacetal
  • HY-102003R
    Rucaparib monocamsylate (Standard)

    AG014699 monocamsylate (Standard); PF-01367338 monocamsylate (Standard)

    		 Reference Standards PARP Cancer
    Rucaparib monocamsylate (Standard) is the analytical standard of Rucaparib monocamsylate (HY-102003). This product is intended for research and analytical applications. Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a Ki of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research .
    Rucaparib monocamsylate (Standard)
  • HY-402202
    (2R,3S,4R,5R)-GlcAc-GlcA

    		Drug Intermediate Cancer
    (2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative that can be used in the synthesis of ADC linkers .
    (2R,3S,4R,5R)-GlcAc-GlcA
  • HY-E71166
    1,5-Anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)

    		Biochemical Assay Reagents Others
    1,5-Anhydro-D-fructose reductase (1,5-Anhydro-D-mannitol-forming) (EC 1.1.1.292) belongs to the GFO/IDH/MocA protein family. It can also reduce 1,5-Anhydro-D-fructose-2,3-diketooses and 2-keto aldoses (called ketones), such as D-glucose ketone (D-arabino-hexose-2-ketoose) and 6-deoxy-D-glucose ketone. It cannot reduce common aldoses and ketoses, nor can it reduce non-glucose aldehydes and ketones.
    1,5-Anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming)
  • HY-180388
    Stibophen

    		Fructose-1,6-bisphosphate aldolase Parasite Phosphatase Infection
    Stibophen is a potent antiparasitic agent is effective against Litomosoides carinii, Dipetalonema witei, and Brugia pahangi. Stibophen inhibits lactate accumulation and phosphofructokinases (PFK) activity in adult filariids. Stibophen also inhibits Ascaris and Hymenolepis diminuta PFK without inhibiting mammalian liver PFK. Stibophen can be used for the research of schistosomiasis and filariid infections .
    Stibophen

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