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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Hippo (MST)
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Hippo (MST)" in MCE Product Catalog:
2
2 Cited Publications
Target:
Research Areas:
SBP-3264 is a YAP activator and STK/MST inhibitor with IC50 values of 36 nM against STK3/MST2 and 24 nM against STK4/MST1. SBP-3264 modulates the Hippo signaling pathway. SBP-3264 can be used for the research of acute myeloid leukemia .
2
2 Cited Publications
Cat. No.: HY-P74742
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: STK4; Kinase Responsive To Stress 2; Serine/Threonine Kinase 4; Mammalian Sterile 20-Like 1; MST1; STE20-Like Kinase MST1; KRS2; Non-Specific Serine/Threonine Protein Kinase; YSK3; Hippo (Drosophila) Homolog; Mammalian STE20-Like Protein Kinase 1; Yeast S
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-E70801
Target:
Research Areas:
MST2 is a class of serine/threonine protein kinases, which plays the central roles in the Hippo pathway controlling the cell proliferation, differentiation, and apoptosis during development. Biotin-MST2 Recombinant Human Active Protein Kinase is a recombinant MST2 protein that can be used to study MST2-related functions, and is biotinylated .
Cat. No.: HY-186148
CAS No.: 3081701-84-7
Target:
Research Areas:
YL-602 is an orally active Hippo pathway activator. YL-602 activates the Hippo pathway via MST1/2, with downstream pathway activation. YL-602 inhibits YAP and CTGF expression in cells irrespective of cell density and serum presence. YL-602 induces tumor cell apoptosis and inhibits colony formation. YL-602 suppresses tumor growth in mice. YL-602 can be used for the research of cancer, such as breast cancer .
Cat. No.: HY-P702744
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: STK4; Kinase Responsive To Stress 2; Serine/Threonine Kinase 4; Mammalian Sterile 20-Like 1; MST1; STE20-Like Kinase MST1; KRS2; Non-Specific Serine/Threonine Protein Kinase; YSK3; Hippo (Drosophila) Homolog; Mammalian STE20-Like Protein Kinase 1; Yeast S
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
