4 Results for "

Hippocampal plasticity

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Hippocampal plasticity" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-120051
CAS No.: 1398496-82-6
Purity:  98.40%
Synonyms: S44819; Egis-13529
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy .
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Cat. No.: HY-P3247
CAS No.: 444073-04-5
Target:  

Insulin Receptor

[D-Ala2]-GIP (human) is a GIP receptor agonist (EC50 = 630 pM). [D-Ala2]-GIP (human) improves glucose tolerance. [D-Ala2]-GIP (human) shows neuroprotective activity in MPTP (HY-W114750)-induced Parkinson's disease model. [D-Ala2]-GIP (human) also improves cognitive function and hippocampal synaptic plasticity in obese diabetic rats. [D-Ala2]-GIP (human) can be used for research of type 2 diabetes, Parkinson's disease, etc
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Cat. No.: HY-P3340
CAS No.: 189224-35-9
Target:  

iGluR

Research Areas:  

Neurological Disease

Leptin (116-130) is a bioactive leptin fragment. Leptin (116-130) promotes AMPA receptor trafficking to synapses and facilitate activity-dependent hippocampal synaptic plasticity. Leptin (116-130) prevents hippocampal synaptic disruption and neuronal cell death in models of amyloid toxicity. Leptin (116-130) has the potential for the research of Alzheimer's disease (AD) .
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Cat. No.: HY-W110130
CAS No.: 3322-62-1
Synonyms: Octadec-9-enamide
Target:  

PPAR

Research Areas:  

Neurological Disease

(E/Z)-Oleamide (Octadec-9-enamide) is a PPARα ligand in hippocampal nuclei. (E/Z)-Oleamide can be isolated from plant Galium aparine L. (GA). (E/Z)-Oleamide controls hippocampal plasticity via transcriptional activation of CREB, and regulates feeding and sexual behavior in rats .
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