Hsp60

By Targets:	HSP (6) Antibiotic (1) Apoptosis (1) Bacterial (1) HIF/HIF Prolyl-Hydroxylase (1) Influenza Virus (1) Mitochondrial Metabolism (1) Oxidative Phosphorylation (1) Potassium Channel (1) Small Interfering RNA (siRNA) (3) β-catenin (1)
By Research Areas:	Cancer (4) Infection (1) Inflammation/Immunology (1) Metabolic Disease (1)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Targets Recommended: Hsp-targeting Chimeras HSP

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-N6790

Nonactin Ammonium ionophore I	Oxidative Phosphorylation Potassium Channel Mitochondrial Metabolism Bacterial Influenza Virus Apoptosis Antibiotic HSP	Infection Cancer
Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K ⁺, and NH₄ ⁺, and it can also inhibit the surface expression of endogenous *HSP60. In addition, Nonactin can induce apoptosis* in β-catenin mutant tumor cells and has anti-tumor activity .

HY-171616

DCEM1	HSP β-catenin	Cancer
DCEM1 binds to heat shock protein 60 (HSP60) and inhibits the interaction of *HSP60* with ClpP, thereby blocking the mitochondrial unfolded protein response. DCEM1 inhibits β-catenin expression and ATP production in PC-3 and TKO cells. DCEM1 can be used in prostate cancer research .

HY-105063

DiaPep277	HSP	Metabolic Disease Inflammation/Immunology
DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes .

HY-W854649

[Au(TPP)]Cl	HSP	Cancer
[Au(TPP)]Cl inhibits the refolding activity of the *Hsp60-Hsp10* complex with significant anticancer activities .

HY-D2360

O-Carboranylphenoxyacetanilide	HIF/HIF Prolyl-Hydroxylase HSP	Cancer
O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC₅₀: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity .

HY-120726

BF844	HSP	Others
BF844 mitigate hearing loss associated with USH3 (usher syndrome type III) mutation CLRN1 (clarin-1) ^N48K. BF844 induces CLRN1 ^N48K transportes to the plasma membrane. BF844 shows significantly preserves hearing in vivo .

HY-RS18520

Hspd1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Hspd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hspd1 Mouse Pre-designed siRNA Set A Hspd1 Mouse Pre-designed siRNA Set A

HY-RS25002

Hspd1 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Hspd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Hspd1 Rat Pre-designed siRNA Set A Hspd1 Rat Pre-designed siRNA Set A

HY-RS06447

HSPD1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HSPD1 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HSPD1 Human Pre-designed siRNA Set A HSPD1 Human Pre-designed siRNA Set A

Cat. No.	Nombre del producto	Type

HY-D2360

O-Carboranylphenoxyacetanilide	Fluorescent Dyes
O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC₅₀: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity .

Cat. No.	Nombre del producto	Target	Research Area

HY-105063

DiaPep277	HSP	Metabolic Disease Inflammation/Immunology
DiaPep277 is a 24 amino acid peptide derived from positions 437-460 in HSP60. DiaPep277 arrests the progression of β-cell destruction in NOD mice. DiaPep277 has an immune modulatory effect on diabetogenic T cells in animal models of diabetes .

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-N6790

Nonactin Ammonium ionophore I	Infection Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Disease Research Anticancer Disease Research Fields Source Classification	Oxidative Phosphorylation Potassium Channel Mitochondrial Metabolism Bacterial Influenza Virus Apoptosis Antibiotic HSP
Nonactin is a macrotetrolide antibiotic and mitochondrial uncoupler with antibacterial, insecticidal, and acaricidal activities. Nonactin acts as an ionophore for monovalent cations, including K ⁺, and NH₄ ⁺, and it can also inhibit the surface expression of endogenous *HSP60. In addition, Nonactin can induce apoptosis* in β-catenin mutant tumor cells and has anti-tumor activity .

Species:	Human (1) Mouse (2)
Tag:	His (2) GST (1)
Source:	E. coli (3)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P73916A

	HSP60 Protein, Mouse (His) 60 kDa heat shock protein, mitochondrial; CPN60; Hsp-60; HspD1	Mouse	E. coli
	The HSP60 protein, together with Hsp10, contributes to the import and assembly of mitochondrial proteins. It ensures correct folding and prevents incorrect folding under stressful conditions. HSP60 Protein, Mouse (His) is the recombinant mouse-derived HSP60, expressed by E. coli, with N-10*His labeled tag.

HY-P73916

	HSP60 Protein, Mouse (His, solution) 1 Publications Verification 60 kDa heat shock protein, mitochondrial; CPN60; Hsp-60; HspD1	Mouse	E. coli
	The HSP60 protein, together with Hsp10, contributes to the import and assembly of mitochondrial proteins. It ensures correct folding and prevents incorrect folding under stressful conditions. HSP60 Protein, Mouse (His, solution) is the recombinant mouse-derived HSP60 protein, expressed by E. coli , with N-His labeled tag.

HY-P73917

	HSP60 Protein, Human (His-GST) 1 Publications Verification 60 kDa heat shock protein, mitochondrial; CPN60; Hsp-60; HspD1	Human	E. coli
	The HSP60 protein is a mitochondrial chaperone that facilitates protein import and assembly. HSP60 Protein, Human (His-GST) is the recombinant human-derived HSP60 protein, expressed by E. coli , with N-His, N-GST labeled tag.

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Host:	Mouse (3) Rabbit (3)
Reactivity:	Human (6) Rat (4) Mouse (6)
Application:	IHC-P (2) ICC/IF (6) IP (5) WB (6) ELISA (1)
Isotype:	IgG (3) IgG1 (1) IgG2b (2)
Conjugation:	Non-conjugated (6)
Clonality:	Monoclonal (4) Recombinant (1)
Modification:	Unmodified (4)

Cat. No.	Compare	Nombre del producto	Application	Reactivity	Image

HY-P80184

	Hsp60 Antibody (YA729) 1 Publications Verification	WB, ICC/IF, IHC-P	Human, Mouse, Rat
	Hsp60 Antibody (YA729) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Hsp60.

HY-P86546

	Hsp60 Antibody (YA6238) HspD1; Hsp60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; Hsp-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Hsp60 Antibody (YA6238) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Hsp60.

HY-P83258

	HspA14 Antibody (YA3003) HspA14; Hsp60; Hsp70L1; Heat shock 70 kDa protein 14; Hsp70-like protein 1; Heat shock protein Hsp60	WB, ICC/IF, IP	Human, Mouse
	HspA14 Antibody (YA3003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA14.

HY-P83258A

	HspA14 Antibody (YA3003)(PBS only) HspA14; Hsp60; Hsp70L1; Heat shock 70 kDa protein 14; Hsp70-like protein 1; Heat shock protein Hsp60	WB, ICC/IF, IP	Human, Mouse
	HspA14 Antibody (YA3003) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA14.

HY-P80711

	Hsp60 Antibody (YA730) HspD1; Hsp60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; Hsp-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, ICC/IF, IP	Human, Mouse, Rat
	Hsp60 Antibody (YA730) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Hsp60.

HY-P80711A

	Hsp60 Antibody (YA730)(PBS only) HspD1; Hsp60; 60 kDa heat shock protein; mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; Hsp-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein	WB, ICC/IF, IP	Human, Mouse, Rat
	Hsp60 Antibody (YA730) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to Hsp60.

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Size	* This product has been "discontinued". Optimized version of product available: / En stock - + Añadir al carrito Obtener un presupuesto

Cat. No.	Nombre del producto		Classification

HY-RS18520

Hspd1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Hspd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS25002

Hspd1 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Hspd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hspd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06447

HSPD1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
HSPD1 Human Pre-designed siRNA Set A contains three designed siRNAs for HSPD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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