1220716-15-3
1220716-15-3
Chemical Structure
O-Carboranylphenoxyacetanilide
- CAS No.: 1220716-15-3
- Formula:C16H24B11NO5
- Molecular Weight:429.29
InChIKey: VCCCHDNBYHUCQT-UHFFFAOYSA-N
SMILES: O=C(NC1=C(O)C=CC(B(O)O)=C1)COC2=CC=C([C]3456[BH]789[BH]3%10%11[BH]4%12%13[BH]5%14%15C67%16([H])[BH]8%17%18[BH]9%10%19[BH]%12%11%20[BH]%14%13%21[BH]%15%16%17[BH]%18%19%21%20)C=C2
Biological Activity: O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity[1].
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O-Carboranylphenoxyacetanilide | O-Carboranylphenoxyacetanilide is a HIF-1α inhibitor and inhibits HIF-1α activation. O-Carboranylphenoxyacetanilide inhibits transcriptional activity of HIF in HeLa cells (IC50: 0.74 μM). O-Carboranylphenoxyacetanilide inhibits HSP60 chaperone activity and HSP60 ATPase activity. | |||||||||||||||||||||
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