15695-27-9
![[Au(TPP)]Cl Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-w854649.gif "[Au(TPP)]Cl Chemical Structure")
15695-27-9
Chemical Structure
[Au(TPP)]Cl
- CAS No.: 15695-27-9
- Formula:C44H28AuClN4
- Molecular Weight:845.14
InChIKey: ZDTIRXCIHICHIF-YKKPBKTHSA-M
SMILES: [N-]12[Au+3]34[N-]5C6=CC=C5C(C7=CC=CC=C7)=C(C=C8)[N]3=C8C(C9=CC=CC=C9)=C1C=CC2=C(C%10=CC=CC=C%10)C%11=[N]4C(C=C%11)=C6C%12=CC=CC=C%12.[Cl-]
Biological Activity: [Au(TPP)]Cl inhibits the refolding activity of the Hsp60-Hsp10 complex with significant anticancer activities[1][2].
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[Au(TPP)]Cl | [Au(TPP)]Cl inhibits the refolding activity of the Hsp60-Hsp10 complex with significant anticancer activities. | |||||||||||||||||||||
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References
- [1]. Qianli Meng, et al. Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics. Front Mol Biosci. 2018 Apr 20:5:35. [Content Brief]
- [2]. Di Hu, et al. Anticancer Gold(III) Porphyrins Target Mitochondrial Chaperone Hsp60. Angew Chem Int Ed Engl. 2016 Jan 22;55(4):1387-91. [Content Brief]
Keywords
