1404506-35-9
1404506-35-9
Chemical Structure
BF844
- CAS No.: 1404506-35-9
- Formula:C21H19ClN4O
- Molecular Weight:378.85
IUPAC Name: 1-(4-chloro-3,5-diphenyl-1H-pyrazolo[3,4-c]pyridazin-1-yl)-2-methylpropan-2-ol
InChIKey: TVNSCKMVODVWRS-UHFFFAOYSA-N
SMILES: CC(O)(C)CN1N=C(C2=CC=CC=C2)C3=C(Cl)C(C4=CC=CC=C4)=NN=C31
Biological Activity: BF844 mitigate hearing loss associated with USH3 (usher syndrome type III) mutation CLRN1 (clarin-1)N48K. BF844 induces CLRN1N48K transportes to the plasma membrane. BF844 shows significantly preserves hearing in vivo[1].
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BF844 | BF844 mitigate hearing loss associated with USH3 (usher syndrome type III) mutation CLRN1 (clarin-1)N48K. BF844 induces CLRN1N48K transportes to the plasma membrane. BF844 shows significantly preserves hearing in vivo. | |||||||||||||||||||||
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