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Results for "

Hydroxyquinoline

" in MedChemExpress (MCE) Product Catalog:

41

Inhibitors & Agonists

5

Biochemical Assay Reagents

11

Peptides

3

Natural
Products

1

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17365
    Octreotide acetate
    15+ Cited Publications

    SMS 201-995 acetate

    		 Somatostatin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
    Octreotide acetate
  • HY-B1005
    8-Hydroxyquinoline
    1 Publications Verification

    8-Quinolinol

    		 Environmental Pollutants Antibiotic Bacterial Cancer
    8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice .
    8-Hydroxyquinoline
  • HY-B0295
    Chloroxine
    2 Publications Verification

    		 Bacterial Antibiotic Parasite Infection
    Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
    Chloroxine
  • HY-125586
    β-Amanitin

    		DNA/RNA Synthesis ADC Payload Cancer
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
    β-Amanitin
  • HY-B1400
    Diiodohydroxyquinoline
    2 Publications Verification

    Iodoquinol; 5,7-Diiodo-8-Hydroxyquinoline; 5,7-Diiodo-8-quinolinol

    		 Environmental Pollutants Parasite SARS-CoV Infection Inflammation/Immunology
    Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .
    Diiodohydroxyquinoline
  • HY-B1212
    Broxyquinoline
    2 Publications Verification

    DibromoHydroxyquinoline; 5,7-Dibromo-8-Hydroxyquinoline

    		 Parasite Influenza Virus Infection
    Broxyquinoline (Dibromohydroxyquinoline) is an effective inhibitor of severe fever with thrombocytopenia syndrome virus (SFTSV) with an IC50 of 5.8 µM. Additionally, Broxyquinoline is an inhibitor of CpACBP1 with an IC50 of 64.9 μM. CpACBP1 is a fatty acyl-CoA binding protein of Cryptosporidium parvum, thus Broxyquinoline has the potential to inhibit parasite growth. Broxyquinoline shows promise for research in the field of infectious diseases .
    Broxyquinoline
  • HY-W001023
    5-Amino-8-hydroxyquinoline

    5A8HQ; 5AHQ

    		 Proteasome NF-κB Cancer
    5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia .
    5-Amino-8-hydroxyquinoline
  • HY-15537
    Tilbroquinol
    1 Publications Verification

    		 Parasite Bacterial Infection
    Tilbroquinol is an orally active halogenated hydroxyquinoline antiprotozoal agent, mainly used for anti-amoebic infections . Tilbroquinol targets intestinal protozoa and Entamoeba histolytica to eliminate parasites in the intestinal lumen. Tilbroquinol can be used in research related to intestinal infections, intestinal amoebiasis and hepatic amoebiasis .
    Tilbroquinol
  • HY-139464
    Q134R

    		Nuclear Factor of activated T Cells (NFAT) Neurological Disease
    Q134R, a neuroprotective hydroxyquinoline derivative that suppresses nuclear factor of activated T cell (NFAT) signaling. Q134R can across blood-brain barrier. Q134R has the potential for Alzheimer's disease (AD) and aging-related disorders research .
    Q134R
  • HY-W005598
    2-Hydroxyquinoline

    		Glycosidase Amylases Metabolic Disease
    2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase with IC50 values of 64.4 µg/mL and 130.5 µg/mL, respectively. 2-Hydroxyquinoline can be used in the study of diabetes .
    2-Hydroxyquinoline
  • HY-P10447
    Plipastatin A1

    Fengycin IX; SNA-60-367-3

    		 Phospholipase Fungal Infection
    Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold [1][2].
    Plipastatin A1
  • HY-32100
    5-Hydroxyquinoline

    Quinolin-5(1H)-one

    		 Biochemical Assay Reagents Others
    5-Hydroxyquinoline is an organic compound commonly used in certain chemical reactions and biological research. It can be used in the manufacture of dyes, cellulase, oxidants and passivators, etc., and is widely used in the pigment, paint and rubber industries. In addition, the compound is also used as the precursor, intermediate and metal ion complexing agent of certain drugs.
    5-Hydroxyquinoline
  • HY-W012037
    8-Hydroxyquinoline hemisulfate
    1 Publications Verification

    8-Quinolinol hemisulfate

    		 Environmental Pollutants Antibiotic Bacterial Infection
    8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
    8-Hydroxyquinoline hemisulfate
  • HY-W008992
    Quinolin-8-ol sulfate hydrate

    8-Hydroxyquinoline sulfate hydrate

    		 Biochemical Assay Reagents Others
    Quinolin-8-ol sulfate hydrate is an organic compound commonly used in dyes and as a raw material for chemical analysis. It can cooperate with metal ions to form dyes, and is widely used in the fields of dyes, printing and textile manufacturing. In addition, the compound also has good toxicity and biocompatibility, and is also used in some medical fields.
    Quinolin-8-ol sulfate hydrate
  • HY-W012037R
    8-Hydroxyquinoline hemisulfate (Standard)

    8-Quinolinol hemisulfate (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
    8-Hydroxyquinoline hemisulfate (Standard)
  • HY-175814
    NLRP3-IN-83

    		NOD-like Receptor (NLR) Pyroptosis Interleukin Related Inflammation/Immunology
    NLRP3-IN-83 is a selective and orally active NLRP3 inflammasome activation inhibitor. NLRP3-IN-83 exhibits good inhibitory IL-1β activity with an IC50 of 1.4 μM by blocking NLRP3, independent of NF-κB signaling. NLRP3-IN-83 only slightly inhibits AIM2 inflammasome pathway, but has no effect on NLRC4 inflammasome. NLRP3-IN-83 prevent cell pyroptosis and exhibits significant anti-inflammatory efficacy in ulcerative colitis model. NLRP3-IN-83 can be used for the study of inflammatory bowel disease (IBD) .
    NLRP3-IN-83
  • HY-P3100
    Orfamide A

    		Parasite Infection
    Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
    Orfamide A
  • HY-B1005R
    8-Hydroxyquinoline (Standard)

    8-Quinolinol (Standard)

    		 Reference Standards Bacterial Antibiotic Cancer
    8-Hydroxyquinoline (Standard) is the analytical standard of 8-Hydroxyquinoline. This product is intended for research and analytical applications. 8-Hydroxyquinoline (8-Quinolinol) is a lipophilic metal chelator that can be used as a fungicide .8-Hydroxyquinoline shows the MIC range of 27.56-55.11 μM (4-8 μg/mL) against the clinical isolates of Neisseria gonorrhoeae. 8-Hydroxyquinoline can bind to copper form complexes and transport copper into cells. 8-Hydroxyquinoline increases in the number of micronucleated polychromatic erythrocytes and can also make hair depigmented in mice .
    8-Hydroxyquinoline (Standard)
  • HY-W016840
    8-Hydroxyquinoline-2-carbaldehyde

    		Biochemical Assay Reagents Others
    8-Hydroxyquinoline-2-carbaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    8-Hydroxyquinoline-2-carbaldehyde
  • HY-B1400R
    Diiodohydroxyquinoline (Standard)

    Iodoquinol (Standard); 5,7-Diiodo-8-Hydroxyquinoline (Standard); 5,7-Diiodo-8-quinolinol (Standard)

    		 Reference Standards Parasite SARS-CoV Infection Inflammation/Immunology
    Diiodohydroxyquinoline (Standard) is the analytical standard of Diiodohydroxyquinoline. This product is intended for research and analytical applications. Diiodohydroxyquinoline (Iodoquinol, 5,7-Diiodo-8-hydroxyquinoline, 5,7-Diiodo-8-quinolinol) has an orally active and satisfactory antiparasitic properties. Diiodohydroxyquinoline exhibits mutagenic potential in mice and potent anti-SARS-CoV-2 activity with an EC50 value of 1.38 μM in VeroE6 cells. Diiodohydroxyquinoline's antimutagen is ascorbic acid. Diiodohydroxyquinoline is promising for research in inflammationin, testinal amebiasis, amebic liver abscess and chronic nonspecific diarrheas .
    Diiodohydroxyquinoline (Standard)
  • HY-158104
    LPPM-8

    		ATF6 Others
    LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
    LPPM-8
  • HY-172041
    PB-22 6-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 6-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 6-Hydroxyquinoline isomer
  • HY-172042
    PB-22 7-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 7-Hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 7-Hydroxyquinoline isomer
  • HY-172040
    PB-22 5-Hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    PB-22 5-hydroxyquinoline isomer is a structural isomer of PB-22. PB-22 is a cannabinoid.
    PB-22 5-Hydroxyquinoline isomer
  • HY-172035
    5-Fluoro PB-22 5-hydroxyquinoline isomer

    		Cannabinoid Receptor Neurological Disease
    5-Fluoro PB-22 5-hydroxyquinoline isomer is a synthetic cannabinoid.
    5-Fluoro PB-22 5-hydroxyquinoline isomer
  • HY-W710247
    3-Hydroxyquinoline-d6

    Quinolin-3-ol-d6

    		 Isotope-Labeled Compounds Others
    3-Hydroxyquinoline-d6 (Quinolin-3-ol-d6) is the deuterium labeled 3-Hydroxyquinoline (HY-W008203).
    3-Hydroxyquinoline-d6
  • HY-145482R
    W36017 (Standard)

    		Drug Metabolite Reference Standards Neurological Disease
    8-Hydroxyquinoline (hemisulfate) (Standard) is the analytical standard of 8-Hydroxyquinoline (hemisulfate). This product is intended for research and analytical applications. 8-Hydroxyquinoline hemisulfate (8-Quinolinol hemisulfate) is a monoprotic bidentate chelating agent, exhibits antiseptic, disinfectant, and pesticide properties, functioning as a transcription inhibitor.
    W36017 (Standard)
  • HY-118288
    Aurachin B

    		Parasite Infection
    Aurachin B is an alkaloid with a 3-hydroxyquinoline N-oxide core .
    Aurachin B
  • HY-W288349
    8-Quinolinyl β-D-glucopyranoside

    		Biochemical Assay Reagents Others
    8-Quinolinyl β-D-glucopyranoside is an 8-hydroxyquinoline glucoconjugate that can be cleaved in vitro by β-glucosidase .
    8-Quinolinyl β-D-glucopyranoside
  • HY-B0295R
    Chloroxine (Standard)

    		Reference Standards Bacterial Antibiotic Parasite Infection
    Chloroxine (Standard) is the analytical standard of Chloroxine. This product is intended for research and analytical applications. Chloroxine is one of the important 8-hydroxyquinoline derivative. Chloroxine has effective antibacterial, antifungal, antiprotozoal and antiamoebic activities, especially used in treating the intestinal amebiasis. Chloroxine is also used in the treatment of dandruff and seborrheic dermatitis of the scalp .
    Chloroxine (Standard)
  • HY-157142
    Antibacterial agent 165

    		Bacterial Infection
    Antibacterial agent 165 (compound 3), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 165 inhibits methicillin-resistant Staphylococcus aureus (MRSA) .
    Antibacterial agent 165
  • HY-157141
    Antibacterial agent 163

    		Bacterial Infection
    Antibacterial agent 163 (compound 1), a hydroxyquinoline derivative, is a potent bacterial inhibitor. Antibacterial agent 163 inhibits methicillin-resistant Staphylococcus aureus (MRSA) .
    Antibacterial agent 163
  • HY-172036
    5-Fluoro PB-22 6-hydroxyquinoline isomer

    		Drug Isomer Neurological Disease
    5-Fluoro PB-22 N-(3-fluoropentyl) isomer is a structural isomer of 5-Fluoro PB-22.
    5-Fluoro PB-22 6-hydroxyquinoline isomer
  • HY-W016535R
    7-Chloroquinolin-4-ol (Standard)

    7-Chloro-4-Hydroxyquinoline (Standard)

    		 Reference Standards
    7-Chloroquinolin-4-ol (Standard) is the analytical standard of 7-Chloroquinolin-4-ol. This product is intended for research and analytical applications.
    7-Chloroquinolin-4-ol (Standard)
  • HY-172037
    5-Fluoro PB-22 7-hydroxyquinoline isomer

    		Cannabinoid Receptor Neurological Disease
    5-Fluoro PB-22 7-hydroxyquinoline isomer is a synthetic cannabinoid.
    5-Fluoro PB-22 7-hydroxyquinoline isomer
  • HY-W001023A
    5-Amino-8-hydroxyquinoline dihydrochloride

    5A8HQ dihydrochloride; 5AHQ dihydrochloride

    		 Proteasome NF-κB Cancer
    5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) dihydrochloride is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline dihydrochloride can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline dihydrochloride can be used for the research of cancer, such as leukemia .
    5-Amino-8-hydroxyquinoline dihydrochloride
  • HY-W051530
    8-Methoxyquinoline

    		Drug Derivative Cancer

    8-Methoxyquinoline is a structural analogue of 8-hydroxyquinoline (HY-B1005). 8-Methoxyquinoline does not bind copper. 8-Methoxyquinoline could neither inhibit the chymotrypsin-like activity of the proteasome in breast cancer cell cultures nor induce cancer cell death. 8-Methoxyquinoline can be used in the research of breast cancer .
    8-Methoxyquinoline
  • HY-W015237R
    2-Oxo-1,2-dihydroquinoline-4-carboxylic acid (Standard)

    2-Hydroxyquinoline-4-carboxylic acid (Standard)

    		 Reference Standards
    2-Oxo-1,2-dihydroquinoline-4-carboxylic acid (Standard) is the analytical standard of 2-Oxo-1,2-dihydroquinoline-4-carboxylic acid. This product is intended for research and analytical applications.
    2-Oxo-1,2-dihydroquinoline-4-carboxylic acid (Standard)
  • HY-P11783
    Surfactin C2

    		Fungal Infection
    Surfactin C2 is a lipopeptide produced by Bacillus subtilis A18 with antifungal activity. Surfactin C2 acts against Heterobasidion annosum and Heterobasidion parviporum. Surfactin C2 exerts its activity mainly through membrane‑active effects to disrupt fungal cell structures and inhibit mycelial growth. Surfactin C2 can be used for the research of butt rot and root rot of conifers .
    Surfactin C2
  • HY-P2209
    Nummularine B

    Daechuine S27; N-Demethylamphibine H

    		 Parasite Phosphodiesterase (PDE) Infection
    Nummularine B (Daechuine S27; N-Demethylamphibine H) is an anti-parasite agent. Nummularine B inhibits calmodulin-dependent phosphodiesterase activity with an IC50 of 16.8 μM. Nummularine B inhibits the growth of Plasmodium and Leishmania donovani in vitro. Nummularine B inhibits the calmodulin-dependent activity of actomyosin Ca 2+-ATPase. Nummularine B is applicable to research related to malaria and visceral leishmaniasis .
    Nummularine B
  • HY-P4948
    Coumarin-Phalloidin

    		Biochemical Assay Reagents Others
    Coumarin-phalloidin is a kind of phalloidin labeled with Coumarin (HY-N0709). Coumarin-phalloidin is a new type of actin probe that can be used for triple immunofluorescence microscopic observation of the cell skeleton .
    Coumarin-Phalloidin

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