13207-66-4
13207-66-4
Chemical Structure
5-Amino-8-hydroxyquinoline
Synonym(s): 5A8HQ; 5AHQ
- CAS 番号: 13207-66-4
- Formula:C9H8N2O
- Molecular Weight:160.18
IUPAC Name: 5-aminoquinolin-8-ol
InChIKey: YDEUKNRKEYICTH-UHFFFAOYSA-N
SMILES: NC1=C2C=CC=NC2=C(O)C=C1
Biological Activity: 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
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5-Amino-8-hydroxyquinoline | 95.0% | 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.95
HY-W001023A5-Amino-8-hydroxyquinoline dihydrochloride -
Similarity Score 0.89
HY-B0963Cloxiquine -
Similarity Score 0.89
HY-W2427094-Chloroquinolin-8-ol -
Similarity Score 0.88
HY-W018397Tiliquinol -
Similarity Score 0.85
HY-B1005R8-Hydroxyquinoline (Standard) -
Similarity Score 0.85
HY-W016794NSC3852 -
Similarity Score 0.85
HY-W001604Quinolin-5-amine -
Similarity Score 0.85
HY-W0073178-Aminoquinoline -
Similarity Score 0.84
HY-321005-Hydroxyquinoline -
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