13207-66-4
Chemical Structure
5-Amino-8-hydroxyquinoline
Synonym(s): 5A8HQ; 5AHQ
- CAS No.: 13207-66-4
- Formula:C9H8N2O
- Molecular Weight:160.18
IUPAC Name: 5-aminoquinolin-8-ol
InChIKey: YDEUKNRKEYICTH-UHFFFAOYSA-N
SMILES: NC1=C2C=CC=NC2=C(O)C=C1
Biological Activity: 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia[1].
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5-Amino-8-hydroxyquinoline | 95.0% | 5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. 5-Amino-8-hydroxyquinoline can inhibit NF-κB activity and induce cancer cells death and shows low cytotoxicity towards normal hematopoietic cells. 5-Amino-8-hydroxyquinoline can be used for the research of cancer, such as leukemia. | ||||||||||||||||||||
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Keywords