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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
219 Results for "
Hydroxysteroid Dehydrogenase
" in MedChemExpress (MCE) Product Catalog:
Products (219)
219 Results for "Hydroxysteroid Dehydrogenase" in MCE Product Catalog:
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Diethylstilbestrol is a non-steroidal female hormone that has oral activity and can act on menopausal and postmenopausal disorders. Diethylstilbestrol can induce DNA oxidation and Apoptosis of spermatogonial stem cells. Diethylstilbestrol can induce thymocyte Autophagy Diethylstilbestrol is a 11β-hydroxysteroid dehydrogenase 2 (HSD11B2) inhibitor. .
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Human Gut Microbiota Metabolites Immune System Disorder Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields Endocrinology Steroids
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2 Cited Publications
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BI 3231, a chemical probe, is a potent and selective hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) inhibitor, with IC50s of 1 and 13 nM for hHSD17B13 and mHSD17B13, respectively. BI 3231 has the potential for the research of nonalcoholic steatohepatitis (NASH) and other liver diseases .
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1 Cited Publications
Cat. No.: HY-18055
CAS No.: 376638-65-2
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BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM.
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1 Cited Publications
Cat. No.: HY-P81196
Synonyms: 3BHS1_HUMAN; 3 beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-isomerase type 1; beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-isomerase type I; 3-beta-HSD I; 3-beta-hydroxy-5-ene steroid Dehydrogenase 1; 3-beta-hydroxy-Delta(5)-steroid Dehydrogenase 1; EC:1.1.1.145; 3-beta-Hydroxysteroid 3-Dehydrogenase 1; EC:1.1.1.270; Delta-5-3-ketosteroid isomerase; Dihydrotestosterone oxidoreductase. EC:1.1.1.210; Steroid Delta-isomerase 1; EC:5.3.3.1; Trophoblast antigen FDO161G; 3BH; HSDB3A;
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1 Cited Publications
Synonyms: 4-Androsten-11β-ol-3,17-dione
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1 Cited Publications
Cat. No.: HY-P72237
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HSD11B1; Short Chain Dehydrogenase/Reductase Family 26C Member 1; Prev. HSD11; HSD11L; Prev. HSD11B; 11-DH; SDR26C1; Short Chain Dehydrogenase/Reductase Family 26C, Member 1; Corticosteroid 11-Beta-Dehydrogenase Isozyme 1; Hydroxysteroid (11-Beta) Dehydro
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3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism .
Cat. No.: HY-18053
CAS No.: 1024033-43-9
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AZD 4017 is a potent, selective 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) inhibitor, with an IC50 of 7 nM.
Synonyms: Δ4-Abiraterone; CB-7627; Abiraterone D4A metabolite
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D4-abiraterone is a major metabolite of abiraterone. D4-abiraterone is an inhibitor of CYP17A1, 3b-hydroxysteroid dehydrogenase (3βHSD) and steroid-5a-reductase (SRD5A) and also an antagonist of androgen receptor.
Cat. No.: HY-159525
CAS No.: 2254299-48-2
Synonyms: Linustedastat; FOR-6219;
OG-6219
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Linustedastatum (Linustedastat; FOR-6219) is an orally active hydroxysteroid 17-beta dehydrogenase 1 (HSD17B1) inhibitor. Linustedastatum can be used for the study of endometriosis .
Cat. No.: HY-160618
CAS No.: 1834601-37-4
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11β-HSD2-IN-2 (compound 3) is a selective inhibitor for 17β-hydroxysteroid dehydrogenase type 2 (17β-HSD2) with an IC50 of 300 nM .
Cat. No.: HY-19325
CAS No.: 1346554-47-9
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SKI2852 is a potent, selective and orally active 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with IC50s of 1.6 nM and 2.9 nM against mHSD1 and hHSD1, respectively .
Cat. No.: HY-W011243
CAS No.: 80-75-1
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11alpha-Hydroxyprogesterone is the analogue of 11beta-Hydroxyprogesterone (HY-N2337), and can be used as an experimental control. 11beta-Hydroxyprogesterone is a potent inhibitors of 11β-Hydroxysteroid dehydrogenase; also activates human mineralocorticoid receptor in COS-7 cells with an ED50 of 10 nM.
Synonyms: VTP-34072
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BI 187004 (VTP-34072) is an 11β-hydroxysteroid dehydrogenase 1 inhibitor for use in diabetes research .
Cat. No.: HY-105128
CAS No.: 80471-63-2
Synonyms: WIN 32729
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Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC50 of 1.45 nM. Epostane blocks ovulation and pregnancy in rats .
Cat. No.: HY-W002734
CAS No.: 87199-18-6
Synonyms: 3-Hydroxybenzeneboronic acid
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
