2 Results for "

ICI169369

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ICI169369" in MCE Product Catalog:

Cat. No.: HY-106805
CAS No.: 85273-96-7
Target:  

5-HT Receptor

Research Areas:  

Others

ICI 169369 is an orally active, specific serotonin and 5-HT2/5-HT1C receptor competitive antagonist. ICI 169369 exhibits Ki values of 1.79 x 10 −8 and 1.58 x 10 −6 M for 5-HT2 and 5-HT1, respectively .
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Cat. No.: HY-111291
CAS No.: 85273-95-6
Target:  

5-HT Receptor

Research Areas:  

Neurological Disease Endocrinology

ICI 169369 (free base) is an orally active, selective and non-competitive antagonist against 5HT receptor. ICI 169369 (free base) blunts the vasopressin (AVP), but not the ACTH, prolactin or growth hormone reponses to insulin-induced hypoglycaemia. ICI 169369 (free base) blocks centrally mediated 5-HT responses and lowers portal pressure in portal hypertensive rats .
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