ICI 169369
ICI 169369 is an orally active, specific serotonin and 5-HT2/5-HT1C receptor competitive antagonist. ICI 169369 exhibits Ki values of 1.79 x 10−8 and 1.58 x 10−6 M for 5-HT2 and 5-HT1, respectively.
For research use only. We do not sell to patients.
- CAS No.: 85273-96-7
- Formula: C19H21ClN2S
- Molecular Weight:344.90
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All 5-HT Receptor Isoforms
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Biological Activity
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5-HT1C Receptor |
Chemical Information
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CAS No. 85273-96-7
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Molecular Weight 344.90
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Formula C19H21ClN2S
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SMILES
CN(C)CCSC1=NC2=CC=CC=C2C=C1C3=CC=CC=C3.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. D S Millson, et al. The effects of a 5-HT2 receptor antagonist (ICI 169,369) on changes in waking EEG, pupillary responses and state of arousal in human volunteers. Br J Clin Pharmacol. 1991 Oct;32(4):447-54. [Content Brief]
[2]. T P Blackburn, et al. In vitro studies with ICI 169,369, a chemically novel 5-HT antagonist. Eur J Pharmacol. 1988 Jun 10;150(3):247-56. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ICI 169369 Related Classifications
HY-106805 Related Classifications
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