1 Result for "

ICMT-IN-35

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ICMT-IN-35" in MCE Product Catalog:

Cat. No.: HY-149709
Target:  

ICMT

Research Areas:  

Cancer

ICMT-IN-35 (compound 10n) is a FTPA-triazole compound and ICMT inhibitor (IC50=0.8 μM). ICMT-IN-35 is taken up by mammalian cells and can prevent K-Ras membrane localization and induce K-Ras mislocalization. Furthermore, ICMT-IN-35 is selectively cytotoxic against ICMT +/+ MEF cells and has low micromolar activity (IC50=0.8 μM) against metastatic pancreatic cancer cell lines .
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