24 Results for "

IL23R

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "IL23R" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0620
CAS No.: 102841-43-0
Mulberroside C is one of the main bioactive components in white mulberry (Morus alba L.). Mulberroside C exhibits antiplatelet, antiviral and neutrophil-regulating activities, and binds to EV-A71 VP1 with a Kd value of 1.289 nM. Mulberroside C reduces the phosphorylation level of ERK, promotes the phosphorylation of IP3RI at the Ser 1756 site, and decreases calcium influx and calcium mobilization. Mulberroside C inhibits the expression of P-selectin (P-selectin). Mulberroside C upregulates the cyclic nucleotide signaling pathway in human platelets. Mulberroside C binds to IL-23R, upregulates the expression of G-CSF, GM-CSF and RASGRP1, and activates the RAS/ERK signaling pathway. Mulberroside C promotes neutrophil maturation, accelerates the recovery of leukopenia, and enhances the antibacterial activity of neutrophils. Mulberroside C inhibits the replication of hepatitis C virus in replicon cells. Mulberroside C prevents the uncoating and genome release of EV-A71, and inhibits the synthesis of viral proteins and RNA. Mulberroside C can be used in studies related to thrombosis-mediated cardiovascular diseases, chemotherapy- and radiotherapy-induced leukopenia, hepatitis C virus infection, and hand, foot and mouth disease .
loading...
    loading...
Cat. No.: HY-P99737
CAS No.: 1884201-71-1
Synonyms: LY­3074828

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Mirikizumab (LY3074828) is a humanized IgG4 monoclonal antibody that targets the p19 subunit of interleukin 23 (IL-23). Mirikizumab binds to human and monkey IL-23 with high affinity, with Kd values of 21 pM and 55 pM, respectively. By inhibiting the binding of IL-23 to IL-23R, Mirikizumab modulates the immune response and holds potential for research in ulcerative colitis and Crohn's disease .
loading...
    loading...
Cat. No.: HY-P10723
CAS No.: 2894052-23-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC50 of 0.0069 μM .
loading...
    loading...
Cat. No.: HY-174616
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL23R mRNA encodes the human interleukin 23 receptor (IL23R) protein, a subunit of the receptor for IL23A/IL23. IL23R pairs with the receptor molecule IL12RB1/IL12R beta1, and both are required for IL23A signaling.
loading...
    loading...
Cat. No.: HY-RS06742
Research Areas:  

Others

IL23R Human Pre-designed siRNA Set A contains three designed siRNAs for IL23R gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS16795
Research Areas:  

Others

Il23r Mouse Pre-designed siRNA Set A contains three designed siRNAs for Il23r gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-RS23236
Research Areas:  

Others

Il23r Rat Pre-designed siRNA Set A contains three designed siRNAs for Il23r gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
Cat. No.: HY-P992242

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Anti-IL-23R Antibody is a monoclonal antibody that targets IL-23R. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-IL-23R Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
loading...
    loading...
Cat. No.: HY-133552
CAS No.: 2413986-35-1
Purity:  99.13%
Target:  

ROR

Research Areas:  

Inflammation/Immunology

RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A, IL-22, and IL-23R
loading...
    loading...
Cat. No.: HY-P72556
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P73197
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
loading...
    loading...
Cat. No.: HY-P73885
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
loading...
    loading...
Cat. No.: HY-P703678
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
loading...
    loading...
Cat. No.: HY-P73886
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P75857
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P73196
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P700746
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P70680
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P78470
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...
Cat. No.: HY-P701011
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 Receptor; Interleukin 23 Receptor; IL23RL1-THE1A; Interleukin-23 Receptor; PSORS7; IL-23R
Species:  
Source:  
loading...
    loading...