1 Result for "

IRF-Luc-THP-1 cells

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "IRF-Luc-THP-1 cells" in MCE Product Catalog:

Cat. No.: HY-187227
STING-IN-19 is a STING inhibitor with a Kd value of 2.31 μM for human STING. STING-IN-19 inhibits the activation of TBK1 and IRF3 by binding to STING, thereby suppressing the activation of downstream signaling pathways. STING-IN-19 reduces the levels of key inflammatory cytokines IL-1β, IL-6 and TNF-α in colonic tissues and serum of mice with ulcerative colitis. STING-IN-19 can be used in studies related to ulcerative colitis .
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