1 Result for "

IkT148009

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "IkT148009" in MCE Product Catalog:

Cat. No.: HY-148794
CAS No.: 2031185-00-7
Purity:  98.42%
Synonyms: IkT-148009
Target:  

c-Met/HGFR Bcr-Abl

Research Areas:  

Neurological Disease Cancer

Risvodetinib (IkT-148009) is an orally active, selective and brain-penetrant protein tyrosine kinase inhibitor, displaying excellent target efficacy against c-Abl1, c-Abl2/Arg with IC50 values of 33 nM, 14 nM, respectively. Risvodetinib suppresses c-Abl activation and substantially protects dopaminergic neurons from degeneration in mouse models of both inherited and sporadic Parkinson’s disease (PD), which is promising for research in the field of PD .
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