1 Result for "

JNJ55308942

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNJ55308942" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-123857
CAS No.: 2166558-11-6
Purity:  99.82%
JNJ-55308942 is a high-affinity, selective, brain-penetrant P2X7 functional antagonist (hP2X7: IC50=10 nM, Ki=7.1 nM; rP2X7: IC50=15 nM, Ki=2.9 nM). JNJ-55308942 is orally bioavailable, binds to brain P2X7 and blocks IL-1β release from adult rodent brain .
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