1 Result for "

JWU-A021

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JWU-A021" in MCE Product Catalog:

Cat. No.: HY-118092
CAS No.: 1403610-23-0
Research Areas:  

Metabolic Disease

JWU-A021 is a GLP-1 secretagogue with an EC50 of 1.9 μM. JWU-A021 activates the TRPA1 cation channel to promote calcium ion influx and increase intracellular calcium levels in enteroendocrine cells and TRPA1-transfected cells. By activating the TRPA1 channel, JWU-A021 stimulates the secretion of GLP-1 from intestinal enteroendocrine cells and intestinal L cells. JWU-A021 is applicable to research related to type 2 diabetes .
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