5 Results for "

Juglone

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "Juglone" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N6949
CAS No.: 481-39-0
Synonyms: 5-Hydroxy-1,4-naphthalenedione
Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
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3
3 Cited Publications
Cat. No.: HY-N1881
CAS No.: 6665-67-4
4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a type of flavonoid compound. 4',5-Dihydroxyflavone can inhibit various oxidases and its IC50 values for collagenase A (ColA) and α-glucosidase are less than 1 μM and 66 μM respectively; for soybean lipoxygenase-1 (LOX-1), its Ki value is 102.6 μM. 4',5-Dihydroxyflavone can be used in studies on anti-toxicity and anti-diabetes .
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Cat. No.: HY-N6949R
CAS No.: 481-39-0
Synonyms: 5-Hydroxy-1,4-naphthalenedione (Standard)
Juglone (Standard) is the analytical standard of Juglone. This product is intended for research and analytical applications. Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
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Cat. No.: HY-N10200
CAS No.: 68594-15-0
2,7-Dimethoxy-6-(1-acetoxyethyl)juglone is a naphthoquinone derivative found in the fungus Kirschsteiniothelia species .
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Cat. No.: HY-184419
Target:  

STAT Apoptosis

Research Areas:  

Cancer

YZZ-24 is a highly potent and selective STAT3 inhibitor featuring a Ki of 0.26 μM. YZZ-24 directly binds to STAT3 (STAT3 SH2 domain) and effectively inhibits STAT3 phosphorylation at tyrosine 705 (p-STAT3 Tyr705) and STAT3 phosphorylation at serine 727 (p-STAT3 Ser727), thereby blocking downstream oncogenic signaling and inducing apoptosis, while having minimal impact on upstream kinases. YZZ-24 can be used in colorectal cancer research .
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