481-39-0
481-39-0
Chemical Structure
Juglone
Synonym(s): 5-Hydroxy-1,4-naphthalenedione
- CAS No.: 481-39-0
- Formula:C10H6O3
- Molecular Weight:174.16
IUPAC Name: 5-hydroxynaphthalene-1,4-dione
InChIKey: KQPYUDDGWXQXHS-UHFFFAOYSA-N
SMILES: O=C(C1=C2C=CC=C1O)C=CC2=O
Biological Activity: Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity [1][2][3].
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Juglone | 99.77% | Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity . | ||||||||||||||||||||
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Juglone (Standard) | ≥98% | Juglone (Standard) is the analytical standard of Juglone. This product is intended for research and analytical applications. Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity . | ||||||||||||||||||||
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References
- [1]. Zmantar T, et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. Microb Pathog. 2016 Dec;101:44-49. [Content Brief]
- [2]. Ji YB, et al. Juglone-induced apoptosis in human gastric cancer SGC-7901 cells via the mitochondrial pathway. Exp Toxicol Pathol. 2011 Jan;63(1-2):69-78. [Content Brief]
- [3]. Peng X, et al. Juglone prevents metabolic endotoxemia-induced hepatitis and neuroinflammation via suppressing TLR4/NF-κB signaling pathway in high-fat diet rats. Biochem Biophys Res Commun. 2015 Jul 3;462(3):245-50. [Content Brief]
