6665-67-4
Chemical Structure
4',5-Dihydroxyflavone
- CAS No.: 6665-67-4
- Formula:C15H10O4
- Molecular Weight:254.24
IUPAC Name: 5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
InChIKey: OKRNDQLCMXUCGG-UHFFFAOYSA-N
SMILES: O=C1C=C(C2=CC=C(O)C=C2)OC3=CC=CC(O)=C13
Biological Activity: 4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a type of flavonoid compound. 4',5-Dihydroxyflavone can inhibit various oxidases and its IC50 values for collagenase A (ColA) and α-glucosidase are less than 1 μM and 66 μM respectively; for soybean lipoxygenase-1 (LOX-1), its Ki value is 102.6 μM. 4',5-Dihydroxyflavone can be used in studies on anti-toxicity and anti-diabetes[1][2][3].
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4',5-Dihydroxyflavone | 99.95% | 4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a type of flavonoid compound. 4',5-Dihydroxyflavone can inhibit various oxidases and its IC50 values for collagenase A (ColA) and α-glucosidase are less than 1 μM and 66 μM respectively; for soybean lipoxygenase-1 (LOX-1), its Ki value is 102.6 μM. 4',5-Dihydroxyflavone can be used in studies on anti-toxicity and anti-diabetes. | ||||||||||||||||||||
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- [1]. Ribeiro D, et al. Inhibition of LOX by flavonoids: a structure-activity relationship study. Eur J Med Chem. 2014 Jan 24;72:137-45. [Content Brief]
- [2]. Proença C, et al. α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1216-1228. [Content Brief]
Keywords
