2 Results for "

Ki20227

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ki20227" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-10408
CAS No.: 623142-96-1
Purity:  99.51%
Target:  

c-Fms VEGFR c-Kit PDGFR

Research Areas:  

Inflammation/Immunology

Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction .
loading...
    loading...
Cat. No.: HY-10408R
CAS No.: 623142-96-1
Ki20227 (Standard) is the analytical standard of Ki20227 (HY-10408). This product is intended for research and analytical applications. Ki20227 is an orally active and highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction .
loading...
    loading...