23 Results for "

LRR

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "LRR" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-115391
CAS No.: 109358-46-5
Synonyms: Boc-Leu-Arg-Arg-AMC
Research Areas:  

Others

Boc-LRR-AMC (Boc-Leu-Arg-Arg-AMC) is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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1
1 Cited Publications
Cat. No.: HY-129087
CAS No.: 1507370-40-2
Purity:  99.26%
Target:  

Apoptosis

Research Areas:  

Cancer

BC-1258,an F-box/LRR-repeat protein 2 (FBXL2) activator,can stabilize and upregulate FBXL2 levels. BC-1258 induces apoptosis of tumorigenic cells,and profoundly inhibits tumor formation in mice .
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1
1 Cited Publications
Cat. No.: HY-P71598
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Nlrp3; Cias1; Mmig1; Nalp3; Pypaf1; NACHT; LRR and PYD domains-containing protein 3; Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; Mast cell maturation-associated-inducible protein 1; PYRIN-containing APAF1-like protein 1
Species:  
Source:  
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Cat. No.: HY-W158030
CAS No.: 5418-95-1
Synonyms: 2GBI
2-Guanidinobezimidazole (2GBI) is a NLRP3 agonist with a KD of 1.29 μM and a selective state-dependent HVCN1 blocker. 2-Guanidinobezimidazole directly binds NLRP3’s LRR domain, enhances NLRP3-ASC and NLRP3-NEK7 interactions, and drives NLRP3 inflammasome activation. 2-Guanidinobezimidazole can be used for the research of LLC lung carcinoma, B16F10 melanoma and ischemic stroke .
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Cat. No.: HY-P99899
CAS No.: 2052591-32-7
Synonyms: PR-1498487

Target:  

ADC Antibodies

Research Areas:  

Cancer

Samrotamab (PR-1498487) is a humanized IgG1-κ chimeric monoclonal antibody targeting LRRC15, with a Kd of 5.42 nM for human LRRC15. Samrotamab disrupts the LRRC15-SCG5 signaling module by binding to a membrane-proximal conformational epitope within the C-terminal leucine-rich repeat region of LRRC15, which locates at the lateral edge of the LRR solenoid while fully exposing the canonical concave β-sheet surface. Samrotamab reduces the viability of bladder cancer cells, inhibits clonogenic growth, impairs cell migration and compromises cell invasion. Samrotamab induces compensatory upregulation of LRRC15 transcripts while suppressing the expression of SCG5 mRNA. Samrotamab is applicable to research on urothelial carcinoma, sarcoma, osteosarcoma and undifferentiated pleomorphic sarcoma .
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Cat. No.: HY-163756
CAS No.: 2769903-01-5
Research Areas:  

Inflammation/Immunology

NLRP3-IN-43 (compound II-8) is a poteny inhibitor of NLRP3 inflammasome activation that binds to the LRR domain, and disrupts NLRP3-NEK7 interaction .
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Cat. No.: HY-RS07805
Research Areas:  

Others

LRR1 Human Pre-designed siRNA Set A contains three designed siRNAs for LRR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS23826
Research Areas:  

Others

Lrr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lrr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-W753820A
Synonyms: Boc-Leu-Arg-Arg-AMC TFA
Research Areas:  

Others

Boc-LRR-AMC TFA (Boc-Leu-Arg-Arg-AMC TFA) is the TFA salt form of Boc-LRR-AMC (HY-115391). Boc-LRR-AMC TFA is a fluorogenic substrate, which can be utilized for detecting the trypsin-like activity of the 26S proteasome or the 20S proteasome core .
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Cat. No.: HY-E70788
Target:  

Ser/Thr Kinase

Research Areas:  

Others

BARK1 Recombinant Human Active Protein Kinase is a membrane LRR-RLK (leucine-rich repeat receptor-like kinase) protein that specifically binds to BAK1 and its homologs .
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Cat. No.: HY-RS17372
Research Areas:  

Others

Lrr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P702003
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NLRP5; NACHT; LRR and PYD domains-containing protein 5; Mater protein homolog; Maternal Antigen that Embryos Require
Species:  
Source:  
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Cat. No.: HY-P72093
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ASPN; ASPN protein; ASPN_HUMAN; Asporin LRR class 1; ; Asporin; Asporin proteoglycan; FLJ20129; LRR class 1; Periodontal ligament associated protein 1; Periodontal ligament-associated protein 1; PLAP 1; PLAP-1; PLAP1; SLRR 1C; SLRR1C; Small leucine rich protein 1C
Species:  
Source:  
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Cat. No.: HY-P705997
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: LRRFIP1; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein
Species:  
Source:  
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Cat. No.: HY-P87287
Synonyms: and NACHT-containing protein antibody; CARD 12 antibody; CARD antibody; CARD LRR and NACHT containing protein 1 antibody; CARD LRR and NACHT containing protein antibody; CARD12 antibody; Caspase recruitment domain containing protein 12 antibody; Caspase recruitment domain family member 12 antibody; Caspase recruitment domain-containing protein 12 antibody; CLAN 1 antibody

Host:  

Rat

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse

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Cat. No.: HY-P85441
Synonyms: LRRFIP1; GCF2; TRIP; Leucine-rich repeat flightless-interacting protein 1; LRR FLII-interacting protein 1; GC-binding factor 2; TAR RNA-interacting protein

Host:  

Mouse

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P702188
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NLRP1; NACHT; LRR and PYD domains-containing protein 1; Caspase recruitment domain-containing protein 7; Death effector filament-forming ced-4-like apoptosis protein; Nucleotide-binding domain and caspase recruitment domain
Species:  
Source:  
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Cat. No.: HY-P702189
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NLRP1; NACHT; LRR and PYD domains-containing protein 1; Caspase recruitment domain-containing protein 7; Death effector filament-forming ced-4-like apoptosis protein; Nucleotide-binding domain and caspase recruitment domain
Species:  
Source:  
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Cat. No.: HY-P81587
Synonyms: SKP2; FBXL1; S-phase kinase-associated protein 2; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; p45skp2

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P85367
Synonyms: SKP2; FBXL1; S-phase kinase-associated protein 2; Cyclin-A/CDK2-associated protein p45; F-box protein Skp2; F-box/LRR-repeat protein 1; p45skp2

Host:  

Mouse

Application:  

WB, IHC-P

Reactivity:  

Mouse, Rat

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