1 Result for "

LYP-IN-4

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LYP-IN-4" in MCE Product Catalog:

Cat. No.: HY-155848
Purity:  98.09%
Target:  

Phosphatase

Research Areas:  

Cancer

LYP-IN-4 (compound D14) is a reversible and selective inhibitor of lymphotyrosine phosphatase (LYP) (Ki=1.34 μM, IC50=3.52μM). LYP-IN-4 inhibits LYP to regulate TCR signaling, up-regulates PD-1/PD-L1 expression, and enhance anti-tumor immunity. LYP-IN-4 activates T cells and inhibits M2 macrophage polarization, inhibits tumor growth in MC38 isogenic mouse models.
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