6 Results for "

Lenalidomide-13C5,15N

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Lenalidomide-13C5,15N" in MCE Product Catalog:

Cat. No.: HY-A0003S2
Synonyms: CC-5013-13C5,15N
Lenalidomide- 13C5, 15N is 15N and 13C labeled Lenalidomide (HY-A0003). Lenalidomide (CC-5013), a derivative of Thalidomide, acts as molecular glue. Lenalidomide is an orally active immunomodulator. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide (CC-5013) specifically inhibits growth of mature B-cell lymphomas, including multiple myeloma, and induces IL-2 release from T cells .
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1
1 Cited Publications
Cat. No.: HY-P10899
Target:  

PROTACs TGF-beta/Smad

Research Areas:  

Endocrinology

ETTAC-2 is a LRG1 PROTAC degrader, degrading LRG1 via the ubiquitin-proteasome pathway with a DC50 value of 8.38 μM. ETTAC-2 penetrates damaged renal cells to reduce the extracellular secretion of LRG1. ETTAC-2 effectively inhibits the TGF-β-Smad3 signaling pathway and diminishes the secretion of fibrosis-associated extracellular matrix proteins. ETTAC-2 degrades LRG1 within fibrotic kidneys and the efficacy in inhibiting the TGF-β-Smad3 pathway both in vitro and vivo. ETTAC-2 can be used for renal fibrosis research .
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Cat. No.: HY-159046S
Research Areas:  

Others

ASGITFSNSGMHW(Val-13C5,15N)R TFA is an isotope of ASGITFSNSGMHWVR TFA labeled with 13C and 15N .
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Cat. No.: HY-P60515S1
Research Areas:  

Others

NQVSLWC-(Leu- 13C6, 15N)-(Val- 13C5, 15N)-K TFA is the 13C- and 15N-labeled NQVSLWCK TFA.
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Cat. No.: HY-P60514S1
Research Areas:  

Others

NQVS-(Leu- 13C6, 15N)-SCA-(Val- 13C5, 15N)-K TFA is the 13C- and 15N-labeled NQVSSCAK TFA.
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Cat. No.: HY-P60516S
Research Areas:  

Others

ASQDISSA-(Leu- 13C6, 15N)-(Val- 13C5, 15N)-WYQQKPGK TFA is the 13C- and 15N-labeled ASQDISSAWYQQKPGK TFA.
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