18 Results for "

Link N peptide

" in MedChemExpress (MCE) Product Catalog:
Products (18)

18 Results for "Link N peptide" in MCE Product Catalog:

Cat. No.: HY-P10954
CAS No.: 197295-74-2
Target:  

p38 MAPK

Research Areas:  

Others

Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases .
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Cat. No.: HY-Y1703
CAS No.: 148893-10-1
Research Areas:  

Others

HATU is a third-generation uronium salt peptide coupling reagent. HATU increases the rate of peptide coupling reactions, activates amino acids, promotes peptide bond formation in both solution-phase and solid-phase synthesis, and also facilitates peptide assembly, fragment coupling, and linear peptide cyclization. HATU can promote the N-acylation of chitosan to generate amide-linked cationic derivatives with a controllable degree of substitution. HATU is commonly used in amine acylation reactions .
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Cat. No.: HY-W012166
CAS No.: 42014-51-7
Synonyms: NHS-Bromoacetate
Research Areas:  

Infection

N-Succinimidyl bromoacetate (NHS-Bromoacetate) is a heterobifunctional crosslinking reagent, mainly used to modify the ɛ-amino group of lysine side chains. By covalently linking its bromoacetyl moiety to the ɛ-amino group of lysine in peptidomimetics, N-Succinimidyl bromoacetate enables their conjugation with thiol-modified nanoparticles via thioether bonds. N-Succinimidyl bromoacetate also performs bromoacetylation modification on carrier proteins, which then forms stable thioether bonds with the thiol groups of cysteine in peptides, thus efficiently preparing soluble peptide-protein conjugates with high substitution ratios. N-Succinimidyl bromoacetate can be used to prepare activated Sepharose derivatives for affinity chromatography, protein affinity labeling reagents, and peptide-protein immunogen conjugates with non-immunogenic linkages. N-Succinimidyl bromoacetate is applicable to studies related to HIV-1 infection and glioblastoma multiforme .
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Cat. No.: HY-151859
CAS No.: 855750-87-7
Purity:  98.40%
Research Areas:  

Others

N3-Gly-Gly-Gly-OH is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-Gly-OH can be used to construct peptide-like ADC linkers via click chemistry .
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Cat. No.: HY-151748
CAS No.: 1994267-98-9
Target:  

ADC Linkers

Research Areas:  

Others

N3-L-Orn(Fmoc)-OH is a non-natural amino acid building block specially designed for solid-phase peptide synthesis and click chemistry. N3-L-Orn(Fmoc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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Cat. No.: HY-151661
CAS No.: 1217462-63-9
Purity:  99.15%
Synonyms: L-azidovaline CHA
Target:  

ADC Linkers

Research Areas:  

Others

N3-L-Val-OH (L-azidovaline) (CHA) is a mixture of N3-L-Val-OH and Cyclohexanamine. N3-L-Val-OH is a non-natural amino acid building block specifically designed for solid-phase peptide synthesis and click chemistry. N3-L-Orn(Fmoc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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Cat. No.: HY-P990088
CAS No.: 2637466-37-4

Target:  

VEGFR PD-1/PD-L1

Research Areas:  

Cardiovascular Disease

Sotiburafusp alfa is a bispecific fusion protein, which is a humanized VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) fused via the peptide linker 101GGSGGSGGSGGSGGS 115 to the N-terminus of the heavy chain (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain variant L352>A, L353>A. Sotiburafusp alfa also functions as a PD-L1 inhibitor and a VEGF inhibitor .
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Cat. No.: HY-151736
CAS No.: 1932432-15-9
Target:  

ADC Linkers

Research Areas:  

Others

N3-L-Dap(Boc)-OH is a non-natural amino acid building block specially designed for solid-phase peptide synthesis and click chemistry. N3-L-Dap(Boc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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Cat. No.: HY-151843
CAS No.: 473430-12-5
Target:  

ADC Linkers

Research Areas:  

Others

N3-L-Lys(Fmoc)-OH is a non-natural amino acid building block specially designed for solid-phase peptide synthesis and click chemistry. N3-L-Lys(Fmoc)-OH can be used as a linker for ADC (antibody-drug conjugate) or for the development of targeting peptides.
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Cat. No.: HY-151859A
CAS No.: 2706488-76-6
Research Areas:  

Others

N3-Gly-Gly-OH DCHA is a click chemistry reagent containing an azide group. N3-Gly-Gly-OH DCHA undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing an alkyne group. N3-Gly-Gly-OH DCHA also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-Gly-Gly-OH DCHA can be used to construct peptide-like ADC linkers via click chemistry .
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Cat. No.: HY-P10055
CAS No.: 2042750-71-8
Synonyms: PSMA-1
Target:  

PSMA

Research Areas:  

Cancer

PSMA-1 is a PSMA targeting peptide (GRFLTGGTGRLLRIS) and can be used for for targeted delivery of glucose-regulated protein (GRP)-silencing siRNAs in PCa cells. PSMA-1 is selected and polyarginine sequences R6 or R9 were added at the C terminus to generate the CTPs. FITC labeling of the peptide with an aminohexanoic acid (Ahx) linker at the N terminus produced FITC-PSMA-1,to track PSMA binding on PCa cells .
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Cat. No.: HY-P3174
CAS No.: 9075-21-2
Target:  

Aminopeptidase

Research Areas:  

Inflammation/Immunology

Pyroglutamate aminopeptidase I is a type of enzyme that cleaves the peptide bond of pyroglutamic acid linked to the N-terminal end of a protein, including some important anti-inflammatory proteins like immunoglobulin .
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Cat. No.: HY-P991158
CAS No.: 2996105-98-5

Target:  

TGF-β Receptor

Research Areas:  

Neurological Disease

Rinvatercept, a fusion protein, is a glycyl (1)-chimeric N-terminal (1-108)-peptide (2-109) combined from the sequences of the extracellular domains of the human ACVR2A/B, and is fused via a G3 peptide linker (110-112) to an immunoglobulin G1 (IgG1) Fc fragment. Rinvatercept can be used for research of neuromuscular disease .
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Cat. No.: HY-118112
CAS No.: 64191-06-6
Research Areas:  

Others

4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
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Cat. No.: HY-149872
CAS No.: 3050582-94-7
Research Areas:  

Others

DCA-RMR1 is a cross-linker. DCA-RMR1 elicits facile bicyclization of native peptides via N-terminus Cys-Cys cross-linking. DCA-RMR1 derivatizes RMR1 with 1,3-dichloroacetone (DCA) .
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Cat. No.: HY-P11662
CAS No.: 521076-75-5
Target:  

Peptides

Research Areas:  

Cancer

NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles
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Cat. No.: HY-P11330
Target:  

Bacterial

Research Areas:  

Infection

L-Ala-D-Glu-m-DAP-D-Ala-D-Ala is a key structured peptide of peptidoglycan of gram-negative bacteria. Peptidoglycan is a network of L-Ala-D-Glu-m-DAP-D-Ala-D-Ala cross-linking the repeated units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc). L-Ala-D-Glu-m-DAP-D-Ala-D-Ala can be used for bacterial metabolic labeling research .
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Cat. No.: HY-P5423D
Target:  

Exosomes

Research Areas:  

Others

Ahx-GALA-Cys is a GALA peptide (HY-P5423) derivative with an N-terminal 6-aminohexanoic acid (Ahx) linker and a C-terminal cysteine residue. Ahx-GALA-Cys possesses strong covalent coupling capacity, which can be used to conjugate fluorophores and targeting ligands for investigating the surface functionalization of small extracellular vesicles (sEV) and lysosomal escape .
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