197295-74-2
Chemical Structure
Link N peptide
- CAS No.: 197295-74-2
- Formula:C81H120N26O29
- Molecular Weight:1921.98
InChIKey: GHPHCEQEWSDUET-MMXWBEGUSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC2=CN=CN2)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)NC([C@H](CC(N)=O)NC([C@H](CC(O)=O)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O
Biological Activity: Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Link N peptide | 99.62% | Link N peptide is a proteoglycan aggregates activator in the extracellular matrix. Link N peptide can selectively activate the p38 mitogen-activated protein kinase (MAPK) pathway to promote the expression of type I and II collagens in human intervertebral disc cells. Link N peptide is promising for research of intervertebral disc degeneration-related diseases. | ||||||||||||||||||||
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References
- [1]. Petit A, et al. Effect of synthetic link N peptide on the expression of type I and type II collagens in human intervertebral disc cells. Tissue Eng Part A. 2011 Apr;17(7-8):899-904. [Content Brief]
- [2]. AlGarni N, et al. Short Link N Stimulates Intervertebral Disc Repair in a Novel Long-Term Organ Culture Model that Includes the Bony Vertebrae. Tissue Eng Part A. 2016 Nov;22(21-22):1252-1257. [Content Brief]
