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  3. NLS peptide

NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles

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NLS peptide

NLS peptide Chemical Structure

CAS No. : 521076-75-5

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Description

NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles[1][2]

Molecular Weight

1271.54

Formula

C53H98N20O14S

CAS No.
Sequence

Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly

Sequence Shortening

CGGGPKKKRKVGG

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Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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NLS peptide
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HY-P11662
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