NLS peptide
NLS peptide is a nuclear localization signal peptide, a short amino acid sequence that can be recognized by nuclear transport machinery (such as the Importin protein complex). NLS peptide can directionally transport the molecules or nanoparticles linked to it into the nucleus, and the N-terminal Cys terminus can be used for subsequent coupling. NLS peptide can be used to construct nucleus-specific imaging probes and nucleus-targeted nanoparticles
For research use only. We do not sell to patients.
- CAS No.: 521076-75-5
- Formula: C53H98N20O14S
- Molecular Weight:1271.54
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
-
CAS No. 521076-75-5
-
Molecular Weight 1271.54
-
Formula C53H98N20O14S
-
Sequence
Cys-Gly-Gly-Gly-Pro-Lys-Lys-Lys-Arg-Lys-Val-Gly-Gly
-
Sequence Shortening
CGGGPKKKRKVGG
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ali MRK, et al. Nuclear Membrane-Targeted Gold Nanoparticles Inhibit Cancer Cell Migration and Invasion. ACS Nano. 2017;11(4):3716-3726. [Content Brief]
[2]. Nitin N, et al. NLS peptide conjugated molecular beacons for visualizing nuclear RNA in living cells. Bioconjug Chem. 2008;19(11):2205-2211. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)